Actively Recruiting
A Clinical Trial Comparing 2x/Day for 30-minutes Use of the Emanate Perio PODS Post-SRP to a Control Group Post-SRP.
Led by McGuire Institute · Updated on 2026-04-27
72
Participants Needed
9
Research Sites
49 weeks
Total Duration
On this page
Sponsors
M
McGuire Institute
Lead Sponsor
E
Emanate Biomedical Inc.
Collaborating Sponsor
AI-Summary
What this Trial Is About
The goal of this clinical trial is to compare safety and to see if individuals with generalized stage III periodontitis that are given a periodontal hydrogel dressing on a wound healing after plaque and tartar have been removed from teeth have greater healing than individuals who are given no treatment after.
CONDITIONS
Official Title
A Clinical Trial Comparing 2x/Day for 30-minutes Use of the Emanate Perio PODS Post-SRP to a Control Group Post-SRP.
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Subjects must read, understand, and sign the informed consent form.
- Age between 30 and 75 years.
- Generalized Stage III periodontitis with at least 8 teeth having interproximal clinical attachment level �3 mm and probing pocket depth between 5 mm and 7 mm, with at least 2 qualifying sites in each arch.
- No more than 6 sites with a pocket depth of 8 mm, and no hopeless teeth with severe mobility or suppuration.
- Minimum of 24 natural teeth, with at least 2 natural teeth per quadrant (excluding third molars).
- Ability to remove all supragingival plaque to allow for thorough periodontal evaluation and digital scanning.
- Agreement to avoid oral rinses or dentifrices with known antibacterial properties.
- Agreement to avoid electric flossers or irrigation devices during the study.
- Ability to perform self-care oral hygiene without assistance.
- Willingness and ability to follow study procedures and instructions.
You will not qualify if you...
- Periodontal surgery, implant placement, or scaling and root planing within 12 months prior to screening, or cleaning within 3 months prior.
- Presence of fixed or removable orthodontic appliances.
- Medical conditions requiring antibiotic prophylaxis before dental treatment.
- Chronic oral lesions causing gum irritation, discomfort, or erosions.
- Oral soft or hard tissue tumors.
- Use of any smoked substances (tobacco, cannabis) within 30 days before screening and during the study.
- Uncontrolled medical conditions such as diabetes, hypertension, or cancer.
- Lactating or pregnant or planning pregnancy during the study.
- Taking medications affecting gum conditions, including corticosteroids, NSAIDs (daily use >3 days), or anticoagulants.
- Regular, prolonged use of oral antimicrobial rinses 30 days before and during the study.
- Use of systemic antibiotics 30 days before screening or anticipated during the trial.
- Participation in other therapeutic clinical studies within 30 days prior to screening.
- Known hypersensitivity to chlorhexidine gluconate, glycerin, polyvinyl alcohol, or ethylene vinyl acetate.
- Any other condition that would prevent completion of the study as judged by the investigator.
AI-Screening
AI-Powered Screening
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Trial Site Locations
Total: 9 locations
1
Regenerative Solutions
Fullerton, California, United States, 92835
Actively Recruiting
2
Shoreline Periodontics and Dental Implants
New London, Connecticut, United States, 06320
Actively Recruiting
3
The Perio Studio
Boston, Massachusetts, United States, 02108
Not Yet Recruiting
4
Metro West Orthodontics & Periodontics
La Vista, Nebraska, United States, 68128
Actively Recruiting
5
Perio Health Professionals
Houston, Texas, United States, 77063
Actively Recruiting
6
Perio Health Professionals
Houston, Texas, United States, 77063
Actively Recruiting
7
Periodontal Center of Excellence, PLLC
Spring, Texas, United States, 77380
Actively Recruiting
8
Glazier Implants + Periodontics
Richmond, Virginia, United States, 23226
Actively Recruiting
9
Seattle Periodontist and Implant Dentistry
Seattle, Washington, United States, 98101
Not Yet Recruiting
Research Team
J
Jill Fuqua
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
SINGLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
2
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