Study of a New Zirconia Dental Device Cemented with PMMA Bone Cement for Treating Missing Teeth in Adults

What this Trial Is About

Researchers are evaluating a new dental device made of zirconia, cemented with Polymethyl methacrylate PMMA bone cement, to explore if it can serve as an additional option for replacing missing teeth. This clinical trial aims to find a faster and possibly more affordable treatment for edentulism, addressing some shortcomings of conventional bridges and dental implants. The study is an early phase interventional trial focusing on fixed prosthodontics. The trial involves placing the zirconia dental device in edentulous areas of the jaw in 48 participants. The device will be cemented with PMMA bone cement and immediately loaded within 0 to 15 days using single crowns or multiple unit bridges made of zirconia, fixed with luting cement. Participants will be randomly assigned to groups based on the location of their missing teeth maxillary anterior, maxillary posterior, mandibular anterior, or mandibular posterior regions. Participants will undergo a Cone Beam Computed Tomography CBCT scan and clinical evaluation before treatment. After device placement, clinical examinations and radiographic evaluations will be conducted every three months for one year to monitor outcomes like bone loss, gum health, oral hygiene, pain, discomfort, dislodgment, and fractures of the dental device. The entire trial spans 16 months, including follow-up periods to assess device performance and safety.

A Clinical Trial of Dental Device Cemented with Polymethyl Methacrylate (PMMA) Bone Cement