Study of Insulin Eye Drops for Treating Dry Eye in Adults with Glaucoma Using Topical Hypotensors

What this Trial Is About

Researchers are evaluating the preliminary effectiveness of insulin eye drops for controlling dry eye disease in patients who use topical hypotensive medications for glaucoma or ocular hypertension. This clinical trial aims to determine whether glaucoma patients treated with these eye drops could benefit compared to using artificial tears. The study is a randomized, single-masked phase 4 trial sponsored by Barbara Burgos Blasco. Participants will be randomly assigned to one of two groups one receiving topical insulin eye drops at a concentration of 1UIml four times daily, and the other receiving artificial tears four times daily as a placebo. The treatment period lasts six months, during which participants will attend follow-up visits at baseline, 1 month, 3 months, and 6 months. During the study, participants will undergo assessments including monitoring changes in dry eye symptoms, corneal staining, corneal sensitivity, conjunctival redness, tear film stability, light dispersion, cytokine levels, and treatment compliance from baseline through six months. These evaluations help researchers understand how the treatments impact dry eye disease. The total participation time includes the initial screening and the six-month treatment and follow-up period.

Clinical Trial to Determine the Efficacy and Safety of Insulin Eye Drops in Dry Eye in Patients with Topical Hypotensors