Actively Recruiting
Clinical Trial of Endoscopically Guided Injection of Exparel (Bupivacaine) for the Treatment of Craniofacial Pain
Led by Stanford University · Updated on 2026-04-27
15
Participants Needed
1
Research Sites
382 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
Exparel has a proven efficacy in providing pain relief for up to 72 hours with a single-dose administration at surgical sites. The study aims to evaluate the effectiveness of endoscopically-guided injection of Exparel (Bupivacaine) for the treatment of craniofacial pain. This study would be conducted in a prospective, randomized, double-blinded, placebo- controlled, and cross-over fashion. We aim to investigate whether the administration of Exparel (Bupivacaine) to the lateral nasal wall may positively impact craniofacial pain and functional outcomes, in patients who experience relief with the topical application of Lidocaine (routinely given prior to almost all ENT endoscopy).
CONDITIONS
Official Title
Clinical Trial of Endoscopically Guided Injection of Exparel (Bupivacaine) for the Treatment of Craniofacial Pain
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Patients with a chief complaint of craniofacial pain including migraine, cluster headache, trigeminal autonomic cephalgia, sphenopalatine ganglioneuraligia, or paroxysmal hemicrania
- Patients seen at Stanford Pain & ENT clinic
You will not qualify if you...
- Age under 18 or over 80 years
- Pregnant women
- Economically disadvantaged individuals unable to afford clinic visits or treatments
- Individuals unable to provide informed consent
- Allergy to bupivacaine
- Unable or unwilling to participate or planning to participate in another clinical study during this study
AI-Screening
AI-Powered Screening
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Trial Site Locations
Total: 1 location
1
Peter H Hwang
Stanford, California, United States, 94304
Actively Recruiting
Research Team
P
Peter Hwang, MD
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
SINGLE
Allocation
NON_RANDOMIZED
Model
CROSSOVER
Primary Purpose
TREATMENT
Number of Arms
2
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