The bacterial etiology of conjunctivitis in early infancy. Eye Prophylaxis Study Group.
M A Krohn, S L Hillier, T A Bell...
https://pubmed.ncbi.nlm.nih.gov/8356971Completed
Phase 3
Age: 0 - 1Year
All Genders
ID00000120
Clinical Trial of Eye Prophylaxis in the Newborn
Led by National Eye Institute (NEI) · Updated on 2009-09-17
N/A
Participants Needed
N/A
Research Sites
N/A
Total Duration
On this page
AI-Summary
What this Trial Is About
To compare the effectiveness of silver nitrate drops, erythromycin ointment, or no medication in preventing neonatal conjunctivitis caused by Chlamydia trachomatis and other eye infections. To compare side effects of the two prophylactic agents.
CONDITIONS
Brief Title
Clinical Trial of Eye Prophylaxis in the Newborn
Who Can Participate
Age: 0 - 1Year
All Genders
Eligibility Criteria
You may qualify if you...
The study included male and female infants delivered at University Hospital in Seattle, Washington. Women were recruited after the 28th week of pregnancy and had to be English-speaking. In addition, they planned to stay at the hospital at least 48 hours following delivery and lived in the greater Seattle metropolitan area. Infants were eligible whether they were delivered vaginally or by cesarean section. Excluded from the study were siblings of infants enrolled in the study, women who were culture-positive for gonorrhea, infants receiving systemic antimicrobials for reasons other than conjunctivitis, women receiving antimicrobials at the time of delivery, and families unlikely to be available for followup after delivery.
You will not qualify if you...
History of severe allergic reactions to study medication Currently pregnant or breastfeeding Recent participation in another clinical trial within the last 30 days Presence of uncontrolled medical conditions that could affect safety
Trial Site Locations
Site Locations not provided
Location information for this trial is currently unavailable.
How is the study designed?
Study Type
INTERVENTIONAL
Masking
DOUBLE
Allocation
RANDOMIZED
Model
N/A
Primary Purpose
TREATMENT
Number of Arms
0
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Published Research Related To This Trial
Randomized trial of silver nitrate, erythromycin, and no eye prophylaxis for the prevention of conjunctivitis among newborns not at risk for gonococcal ophthalmitis. Eye Prophylaxis Study Group.
T A Bell, J T Grayston, M A Krohn...
https://pubmed.ncbi.nlm.nih.gov/8233733