Study Comparing Two Exercise Programs for Adults with Hypertension Sprint Interval Training Versus Moderate-Intensity Continuous Training to Lower Blood Pressure and Improve Health

What this Trial Is About

Researchers are evaluating two types of exercise programs for adults aged 30 to 59 with arterial hypertension but without high cardiovascular risk. The study compares Sprint Interval Training SIT, which involves short bursts of maximum effort, with Moderate-Intensity Continuous Training MICT. The main goal is to see how each exercise type affects 24-hour ambulatory systolic blood pressure after 12 weeks of training. Secondary goals include assessing other blood pressure measures, metabolic factors, body composition, and blood markers like IL-6 and alpha-CGRP. Participants first complete a two-week familiarization period before being randomly assigned to one of two exercise groups. The MICT group cycles continuously at moderate intensity 50-70% of maximum oxygen uptake for 15 to 30 minutes per session. The SIT group performs 2 to 4 maximal cycling sprints lasting 20-30 seconds each, with recovery breaks, totaling up to 15 minutes per session. Both groups train three times per week for 12 weeks under professional supervision, with monitoring of blood pressure, heart rate, and oxygen levels during sessions. During the study, participants undergo evaluations before and after the exercise period. These include ambulatory and office blood pressure monitoring, body measurements, blood tests for metabolic and inflammatory markers, heart and vessel function assessments, and physical fitness tests. The study tracks adherence to training and examines changes in various health parameters to understand the effects of both exercise programs on hypertension. The total participation lasts about 14 weeks, including familiarization and intervention phases.

Clinical Trial in Hypertensive Patients Comparing Two Cardiorespiratory Exercise Protocols, Low-volume Sprint Interval Training (SIT) Versus Moderate-intensity Continuous Training (MICT), to Evaluate Decreases in Ambulatory Blood Pressure and Other Clinical Variables.