Actively Recruiting
The Center for Enhancing Triage and Utilization for Depression and Emergent Suicidality (ETUDES) in Pediatric Primary Care-iCHART Randomized Controlled Trial
Led by University of Pittsburgh · Updated on 2026-06-04
900
Participants Needed
13
Research Sites
N/A
Total Duration
On this page
Sponsors
U
University of Pittsburgh
Lead Sponsor
C
Children's Hospital of Philadelphia
Collaborating Sponsor
AI-Summary
What this Trial Is About
Researchers are evaluating the effectiveness of the iCHART (integrated Care to Help At-Risk Teens) intervention for adolescents aged 12 to 18 who are experiencing depression or suicidal behavior. This study aims to reduce suicide-related events by comparing iCHART to usual treatment in a randomized controlled trial including 900 participants. The study also examines factors that affect treatment response and uses implementation science to assess barriers, facilitators, and outcomes like acceptability and feasibility to support health equity. iCHART combines three main parts: a Safety Planning App that helps providers deliver care through an app instead of paper, a Mental Health Screener questionnaire to personalize treatment plans, and a series of text messages over 2 to 3 weeks to encourage engagement with safety plans and treatment. Participants are randomly assigned to either receive iCHART or treatment as usual, which may include a paper safety plan and standard care from their providers. Participants will be actively involved through mental health assessments at baseline and follow-up points up to 12 months, including evaluations of depression severity and suicidal thoughts and behaviors. The study also tracks service use, app usage, and participants' views on the intervention's acceptability, usability, feasibility, and appropriateness. This comprehensive monitoring helps understand how well iCHART works and informs future use in pediatric care settings.
CONDITIONS
Brief Title
Clinical Trial for Integrated Care to Help At Risk Teen (iCHART) Intervention
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Youth aged 12 to 18 years who speak English
- Youth with current depression or suicidal behavior as defined by specific questionnaire scores or history
- Parents or caregivers aged 18 or older who can provide consent and participate in the study
- Only one parent or caregiver per youth will participate in assessments
- 50% of youth with depression scores will also screen positive for suicide risk
You will not qualify if you...
- Youth currently experiencing a manic or psychotic episode
- Youth with a life-threatening medical condition requiring immediate treatment
- Youth with intellectual or developmental disabilities that prevent understanding study procedures
- Youth without access to a phone or tablet needed for the intervention
- Caregivers who are not biological parents or court-appointed guardians of the youth
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Your Study Journey
Duration - 2 to 4 weeks
Participants are screened for eligibility to participate in the trial.
1 screening and enrollment visit (in-person)
Duration - 2 to 3 weeks
Participants receive either the iCHART intervention, which includes a safety planning app, a mental health screener, and personalized text messages for 2-3 weeks to support engagement, or treatment as usual with standard care such as a paper safety plan. Both groups continue usual care at their pediatric primary care practice.
1 baseline visit and multiple follow-up contacts during intervention period
Duration - Up to 12 months
Participants are monitored for suicide-related events, depression severity, and service utilization over 12 months following treatment to assess the effectiveness and engagement with the intervention or usual care.
Visits at 1 month, 3 months, 6 months, and 12 months follow-up
Trial Site Locations
Total: 13 locations
1
Gibbsboro
Gibbsboro, New Jersey, United States, 08026
Actively Recruiting
2
Conemaugh Memorial Medical Center-Family Medicine
Johnstown, Pennsylvania, United States, 15905
Actively Recruiting
3
CHOP Primary Care, CHOP Campus
Philadelphia, Pennsylvania, United States, 19104
Actively Recruiting
4
Roxborough
Philadelphia, Pennsylvania, United States, 19128
Actively Recruiting
5
CHOP Primary Care, Cobbs Creek
Philadelphia, Pennsylvania, United States, 19139
Actively Recruiting
6
Karabots
Philadelphia, Pennsylvania, United States, 19139
Actively Recruiting
7
Children's Community Pediatrics (CCP) of Children's Hospital of Pittsburgh UPMC
Pittsburgh, Pennsylvania, United States, 15213
Actively Recruiting
8
UPMC Center for Adolescent and Young Adult Health
Pittsburgh, Pennsylvania, United States, 15213
Actively Recruiting
9
UPMC Family Medicine
Pittsburgh, Pennsylvania, United States, 15213
Actively Recruiting
10
Kids Plus Pediatrics (KPP)
Pittsburgh, Pennsylvania, United States, 15217
Actively Recruiting
11
Berks Community Health Center
Reading, Pennsylvania, United States, 19604
Actively Recruiting
12
Springfield
Springfield, Pennsylvania, United States, 19064
Actively Recruiting
13
CHOP Primary Care, West Chester
West Chester, Pennsylvania, United States, 19380
Actively Recruiting
Research Team
B
Brandie George-Milford, MA
How is the study designed?
Study Type
INTERVENTIONAL
Masking
SINGLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
HEALTH_SERVICES_RESEARCH
Number of Arms
2
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