Actively Recruiting

Phase Not Applicable
Age: 20Years - 50Years
All Genders
Healthy Volunteers
NCT07043478

A Clinical Trial to Investigate the Efficacy of Bragg Apple Cider Vinegar on Blood Glucose Control in a Healthy Adult Population

Led by Bragg Live Food Products · Updated on 2026-03-06

24

Participants Needed

1

Research Sites

29 weeks

Total Duration

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Sponsors

B

Bragg Live Food Products

Lead Sponsor

K

KGK Science Inc.

Collaborating Sponsor

AI-Summary

What this Trial Is About

The goal of this clinical study is to investigate the efficacy of a Bragg Apple Cider Vinegar (ACV) liquid on postprandial glucose (PPG) excursion compared to a placebo following a standardized acute carbohydrate load. The main question it aims to answer is: Is there a difference in the incremental area under the curve (iAUC) (from 0 - 120 mins following administration) for venous blood glucose between Bragg ACV liquid and placebo following an acute carbohydrate load. Participants will \[describe the main tasks participants will be asked to consume 750 mg of Bragg Apple Cider Vinegar (ACV) liquid or water and undergo a blood draw to measure glucose, insulin, and future analysis markers.

CONDITIONS

Official Title

A Clinical Trial to Investigate the Efficacy of Bragg Apple Cider Vinegar on Blood Glucose Control in a Healthy Adult Population

Who Can Participate

Age: 20Years - 50Years
All Genders
Healthy Volunteers

Eligibility Criteria

Eligible

You may qualify if you...

  • Males and females aged 20 to 50 years, inclusive
  • Females not of child-bearing potential (sterilized or post-menopausal for at least 1 year) OR females of child-bearing potential with negative pregnancy test and using approved birth control for study duration
  • Hormonal birth control use for at least 3 months if applicable
  • Acceptable birth control methods include hormonal contraceptives, double-barrier method, intrauterine devices, vasectomy of partner (≥6 months), abstinence with agreement to use contraception if sexually active
  • Elevated fasting glucose >5.6 mmol/L but <7.0 mmol/L and/or HbA1c between 6.0-6.4% with two or more markers of metabolic syndrome
  • Stable body weight with less than 5% change in past 3 months
  • Agreement to maintain current lifestyle habits and comply with dietary guidelines
  • Provided voluntary, written informed consent
  • Otherwise healthy as determined by medical history and lab results
Not Eligible

You will not qualify if you...

  • Pregnant, breastfeeding, or planning pregnancy during the study
  • Allergy, sensitivity, or intolerance preventing consumption of study products or standardized meal
  • Poor venous access
  • Current use of medications, supplements, or foods that affect glucose metabolism or investigational product efficacy
  • Unstable metabolic or chronic diseases
  • Current or history of significant gastrointestinal diseases
  • Unstable hypertension unless on stable medication for at least 3 months
  • Diagnosis of Type I or Type II diabetes
  • Significant cardiovascular event in past 6 months unless stable on medication
  • History or diagnosis of kidney or liver disease except symptom-free kidney stones for 6 months
  • Thyroid condition unless stable on medication for at least 3 months
  • Major surgery in past 3 months or planned surgery during study
  • Cancer except basal cell carcinoma excised with no chemo/radiation or cancer in remission >5 years
  • Autoimmune diseases or immune compromise
  • HIV, Hepatitis B or C infection
  • Blood or bleeding disorders
  • Regular cannabinoid use (>1 time/month); occasional users must abstain during study
  • Regular tobacco or nicotine use in past 6 months; occasional users must abstain
  • Alcohol intake >2 standard drinks per day
  • Alcohol or drug abuse within last 12 months
  • Significant abnormal lab results at screening
  • Blood donation within 30 days before baseline or planned during study
  • Participation in other clinical studies within 30 days before baseline
  • Unable to give informed consent
  • Any other condition or lifestyle factor that may affect study completion or pose risk per investigator opinion

AI-Screening

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Trial Site Locations

Total: 1 location

1

KGK Science Inc.

London, Ontario, Canada, N6B3L1

Actively Recruiting

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Research Team

M

Marc Moulin, PhD

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

QUADRUPLE

Allocation

RANDOMIZED

Model

CROSSOVER

Primary Purpose

TREATMENT

Number of Arms

2

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A Clinical Trial to Investigate the Efficacy of Bragg Apple Cider Vinegar on Blood Glucose Control in a Healthy Adult Population | DecenTrialz