Actively Recruiting

Phase Not Applicable
Age: 18Years - 75Years
All Genders
NCT06536010

Clinical Trial Protocol for the Combined Use of VAG in the Treatment of ND-AML

Led by Yang Xiaotian · Updated on 2024-08-02

50

Participants Needed

1

Research Sites

351 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

This is a clinical efficacy study evaluating the VAG regimen in the treatment of newly diagnosed acute myeloid leukemia (AML). The main objectives of the study are to assess the efficacy and safety of the VAG regimen and to explore the synergistic mechanisms of VAG in combating AML.

CONDITIONS

Official Title

Clinical Trial Protocol for the Combined Use of VAG in the Treatment of ND-AML

Who Can Participate

Age: 18Years - 75Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Age between 18 and 75 years, regardless of gender.
  • Diagnosis of AML (excluding APL) according to the 2022 WHO diagnostic criteria.
  • ECOG performance status of 0-2.
  • Effective contraception for females of childbearing potential and males with female partners during treatment and for 6 months after.
  • Expected survival of at least 3 months.
  • Ability to understand and willingness to participate, with signed informed consent.
Not Eligible

You will not qualify if you...

  • Acute promyelocytic leukemia (M3 subtype).
  • Central nervous system leukemia.
  • Severe uncontrolled infection or other major diseases.
  • Heart failure with ejection fraction less than 50% or NYHA class II or above.
  • Impaired liver or kidney function defined by specific laboratory values.
  • HIV positive.
  • Active hepatitis B or C.
  • Pregnant or lactating women.
  • Other conditions deemed unsuitable by the investigator.

AI-Screening

AI-Powered Screening

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Trial Site Locations

Total: 1 location

1

Huai'an Second People's Hospital

Huai'an, Jiangsu, China, 210000

Actively Recruiting

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Research Team

X

Xiaotian Yang

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

NA

Model

SINGLE_GROUP

Primary Purpose

TREATMENT

Number of Arms

1

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