Actively Recruiting

All Genders
NCT00313677

Clinical Trial Readiness for the Dystroglycanopathies

Led by Katherine Mathews · Updated on 2025-07-30

190

Participants Needed

1

Research Sites

1265 weeks

Total Duration

On this page

Sponsors

K

Katherine Mathews

Lead Sponsor

N

National Institute of Neurological Disorders and Stroke (NINDS)

Collaborating Sponsor

AI-Summary

What this Trial Is About

The purpose of the study is to describe the early signs and symptoms of the dystroglycanopathies, and to gather information that will be required for future clinical trials.

CONDITIONS

Official Title

Clinical Trial Readiness for the Dystroglycanopathies

Who Can Participate

All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Elevated CK (creatine kinase)
  • Evidence of a dystroglycanopathy confirmed by muscle pathology review, documented mutation in a known gene, or abnormal alpha-dystroglycan glycosylation in cultured fibroblasts
  • Participants of any age and all racial and ethnic backgrounds are eligible
  • Both males and females will be recruited equally
  • Participants may have varying degrees of muscular weakness but should be in relatively good health
Not Eligible

You will not qualify if you...

History of severe allergic reactions to study medication Currently pregnant or breastfeeding Recent participation in another clinical trial within the last 30 days Presence of uncontrolled medical conditions that could affect safety

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

University of Iowa, 200 Hawkins Drive

Iowa City, Iowa, United States, 52242

Actively Recruiting

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Research Team

C

Carrie Stephan, R.N. M.A.

CONTACT

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

0

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