Actively Recruiting

Phase 2
Age: 6Years - 17Years
All Genders
NCT06372249

A Clinical Trial of Soluble Fiber for Asthma

Led by Phoenix Children's Hospital · Updated on 2026-03-04

105

Participants Needed

1

Research Sites

81 weeks

Total Duration

On this page

Sponsors

P

Phoenix Children's Hospital

Lead Sponsor

N

Northern Arizona University

Collaborating Sponsor

AI-Summary

What this Trial Is About

Randomized controlled trial of soluble fiber (Fruitafit Inulin). Participants will complete an ASA 24 dietary recall questionnaire to access their fiber intake. If eligible for the study, participants will be supplemented to their target fiber dosage with either soluble fiber (Fruitafit Inulin) or placebo. Collection of blood serum, fecal samples, and nasal wash will aid in analyzing the microbes present in one's gut and how fiber and diet may impact it. Thus, allowing researchers to better understand the pathways that may connect diet and asthma and if it is possible to improve asthma by altering one's diet.

CONDITIONS

Official Title

A Clinical Trial of Soluble Fiber for Asthma

Who Can Participate

Age: 6Years - 17Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Between ages 6-17
  • Asthma diagnosis within the last 2 years
  • Fractional excretion of exhaled nitric oxide (FeNO) > 50 ppb OR a clinical history of environmental allergies confirmed by positive skin prick or specific IgE tests to aeroallergens
  • No emergency department visits for asthma in the past 1 month
  • Ability to consume a liquid drink containing fiber or placebo
  • Ability to return for a 4-6 week follow-up visit
  • No special or unique diet
Not Eligible

You will not qualify if you...

  • Cystic fibrosis
  • Bronchiectasis
  • Planned change in asthma medicines other than short-acting bronchodilators over the next 4-6 weeks
  • Baseline estimated daily fiber intake less than or equal to 16 grams as determined by the ASA 24
  • Sibling of a participant already enrolled in the study

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Phoenix Children's

Phoenix, Arizona, United States, 85016

Actively Recruiting

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Research Team

D

Daniel Gastaldo

CONTACT

M

Matthew Rank

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

QUADRUPLE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

TREATMENT

Number of Arms

2

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