Study of Bladder Sensations and Overactive Bladder Severity in Adults with Multiple Sclerosis

What this Trial Is About

Researchers are studying the relationship between how bladder sensations change during filling and the severity of Overactive Bladder OAB symptoms in patients with multiple sclerosis MS. Lower urinary tract symptoms are common in MS, with OAB being the most frequent complaint. This study focuses on bladder sensation progression as a potential factor influencing urinary symptoms in MS patients. Participants will undergo repeated cystometry procedures to assess bladder sensations. The study includes a second cystometry to check the reliability of bladder sensation measurements and a third cystometry combined with a cognitive task STROOP test to evaluate how attention affects bladder sensations. These procedures aim to better understand bladder function and sensation changes in MS. During the study, participants will have bladder sensations measured, focusing on the area under the sensation-capacity curve as the primary outcome. Secondary outcomes include bladder sensitivity. The study involves detailed urodynamic testing and assessments to monitor bladder function and sensations, helping to clarify mechanisms behind bladder disorders in MS. The study runs until February 2027, and participants will be carefully evaluated throughout.

Clinical and Urodynamic Assessment of Bladder Sensation in Multiple Sclerosis