Actively Recruiting

Phase Not Applicable
Age: 18Years +
All Genders
NCT06538376

Clinical Utility of Portable Dynamic Chest X Ray (DDR) in the ICU

Led by Brigham and Women's Hospital · Updated on 2025-10-29

230

Participants Needed

1

Research Sites

202 weeks

Total Duration

On this page

Sponsors

B

Brigham and Women's Hospital

Lead Sponsor

K

Konica Minolta

Collaborating Sponsor

AI-Summary

What this Trial Is About

Dynamic digital radiography (DDR) is a new advanced version of chest radiography that captures dynamic images at a rate of 15 frames per second. It is coupled with an analytical software that allows it to provide more advanced measures of lung motion, ventilation, and perfusion compared to traditional chest radiography. While implementation of DDR fixed machines are beginning elsewhere in the US, this trial involves the first applications of an FDA-approved portable DDR machine, for use at the bedside in the ICU. The goal of this clinical trial is to determine the feasibility and safety of portable DDR technology in the ICU, as well as to evaluate the improved clinical diagnostic value of the portable DDR system over current standards of care. Participants will receive one to three sets of DDR images, which will then be compared to their clinical gold standard exams (such as chest x-rays, CTs, or VQ scans) to assess and improve the precision and accuracy of measurements such as diaphragmatic motion, lung movement, and perfusion.

CONDITIONS

Official Title

Clinical Utility of Portable Dynamic Chest X Ray (DDR) in the ICU

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Adults aged 18 years or older, including both ventilated and non-ventilated patients
  • Likely to have lung or diaphragm problems such as abnormal diaphragm movement, lung aeration issues, pulmonary blood flow problems, increased lung water, or swallowing difficulties
  • Written informed consent provided by the participant or legally authorized representative
Not Eligible

You will not qualify if you...

  • Women who are pregnant, prisoners, or institutionalized individuals
  • Patients for whom additional radiation is not safe
  • Care team does not approve contacting the patient or surrogate
  • Women of child-bearing potential must have a negative pregnancy test to participate

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Brigham and Women's Hospital

Boston, Massachusetts, United States, 02115

Actively Recruiting

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Research Team

G

Gyorgy Frendl, MD PhD

CONTACT

P

Poorva Bagchee, BS

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

NA

Model

SINGLE_GROUP

Primary Purpose

DIAGNOSTIC

Number of Arms

1

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