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ID06538376

Evaluating Portable Dynamic Chest X-Ray DDR for Lung Function Diagnosis in ICU Patients A Study on Feasibility and Improved Diagnostic Accuracy Compared to Standard Imaging

Led by Brigham and Women's Hospital · Updated on 2025-10-29

230

Participants Needed

1

Research Sites

52 weeks

Total Duration

AI-Summary

What this Trial Is About

Researchers are evaluating the use of portable dynamic digital radiography DDR, a new advanced chest X-ray technology, in intensive care unit ICU patients. DDR captures dynamic images of lung motion, ventilation, and perfusion at a high frame rate, potentially providing more detailed and quantitative lung function information compared to traditional chest X-rays. This trial aims to test the feasibility and safety of portable DDR in the ICU and to compare its diagnostic value with current standard imaging methods. Participants will receive one to three sets of DDR scans, including 7-second breathing and breath-holding scans. These images will be compared to gold standard clinical exams such as chest X-rays, CT scans, or ventilation-perfusion VQ scans. The study will observe how DDR performs in diagnosing lung conditions like diaphragmatic dysfunction, pulmonary embolism, and pulmonary edema, alongside routine clinical imaging. Throughout the study, participants will undergo DDR imaging alongside their routine clinical imaging. Researchers will analyze these images to measure lung motion, diaphragmatic movement, and perfusion. The primary outcomes include assessing the precision of DDR in evaluating cardiopulmonary functions related to the diaphragm and lung motion as well as pulmonary blood flow, over a period of up to two months. The study will monitor safety and diagnostic accuracy while patients receive standard care.

CONDITIONS

Brief Title

Clinical Utility of Portable Dynamic Chest X Ray (DDR) in the ICU

Research Team

G

Gyorgy Frendl, MD PhD

P

Poorva Bagchee, BS

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