Actively Recruiting

Phase 1
Age: 18Years - 83Years
All Genders
Healthy Volunteers
NCT07227922

Clofutriben Pharmacokinetics in Patients With Impaired Renal Function

Led by Sparrow Pharmaceuticals · Updated on 2025-12-23

16

Participants Needed

1

Research Sites

30 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

This is a Phase 1, single-center, open-label, single-dose trial. Sixteen participants are planned: 8 participants with moderate renal impairment and 8 matched control participants with normal renal function.

CONDITIONS

Official Title

Clofutriben Pharmacokinetics in Patients With Impaired Renal Function

Who Can Participate

Age: 18Years - 83Years
All Genders
Healthy Volunteers

Eligibility Criteria

Eligible

You may qualify if you...

  • Male and female participants with stable moderate renal impairment (estimated glomerular filtration rate [eGFR]: 30 to <60 mL/min)
  • Matched control participants with normal renal function (eGFR: 290 mL/min) matched by sex, age, and weight
Not Eligible

You will not qualify if you...

  • Participants with medical conditions, medications, or procedures that increase safety risk or are unsuitable for the trial
  • Participants with clinically significant abnormal 12-lead electrocardiogram (ECG), vital signs, or laboratory test results at screening and check-in

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Orlando Clinical Research Center

Orlando, Florida, United States, 32809

Actively Recruiting

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How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

NA

Model

SINGLE_GROUP

Primary Purpose

TREATMENT

Number of Arms

1

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