Actively Recruiting
Closing the GAPS: Guideline Adherence, Prevention and Surveillance in Hereditary Cancer
Led by Nest Genomics · Updated on 2026-02-25
100
Participants Needed
1
Research Sites
81 weeks
Total Duration
On this page
Sponsors
N
Nest Genomics
Lead Sponsor
D
Dana-Farber Cancer Institute
Collaborating Sponsor
AI-Summary
What this Trial Is About
The goal of this clinical trial is to see if a software platform can improve cancer screening in young adults with genetic risk for cancer. The trial will also help improve the software platform (Nest). The main questions it aims to answer are: * Do Nest users know more about their cancer risks and recommended care than non-users? * Do Nest users have less psychological distress than non-users? * Do Nest users share cancer risks with family and other doctors more than non-users? * Are Nest users more likely than non-users to have up-to-date care plans? Researchers will compare Nest users to non-users to see if the Nest users are more likely to do recommended cancer screening. Participants will: * Have a genetic counseling or follow up visit * Take a post-visit survey * Intervention arm only: use the Nest Patient Navigator * Complete screening and follow-up care recommended by doctors
CONDITIONS
Official Title
Closing the GAPS: Guideline Adherence, Prevention and Surveillance in Hereditary Cancer
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Ages 18-49 years, inclusive
- Previous cancer genetic testing showing a pathogenic or likely pathogenic variant that increases cancer risk
- Able to read and speak English
- Receiving care at Dana Farber Cancer Institute
- Not undergoing active cancer therapy at the time of approach
You will not qualify if you...
- Younger than 18 or older than 49 years
- No genetic testing for hereditary cancer syndromes or testing showed no pathogenic or likely pathogenic variant
- Unable to read or speak English
- Not receiving care at Dana Farber Cancer Institute
- Currently undergoing active cancer therapy
AI-Screening
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Trial Site Locations
Total: 1 location
1
Dana Farber Cancer Institute
Boston, Massachusetts, United States, 02215
Actively Recruiting
Research Team
J
Jennifer W Mack, MD
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
SUPPORTIVE_CARE
Number of Arms
2
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