Actively Recruiting
CMR Prognostic Markers in Ischemic Heart Disease
Led by Chinese Academy of Medical Sciences, Fuwai Hospital · Updated on 2026-01-20
1000
Participants Needed
1
Research Sites
1404 weeks
Total Duration
On this page
Sponsors
C
Chinese Academy of Medical Sciences, Fuwai Hospital
Lead Sponsor
N
National Natural Science Foundation of China
Collaborating Sponsor
AI-Summary
What this Trial Is About
Ischemic heart disease (IHD) remains a leading cause of morbidity and mortality worldwide. Accurate risk stratification is essential for guiding clinical management and improving long-term outcomes in patients with ischemic myocardial injury. Cardiovascular magnetic resonance (CMR) imaging provides comprehensive assessment of myocardial structure, function, and tissue characteristics, enabling detailed evaluation of ischemic injury and its consequences. This multicenter, retrospective observational study aims to investigate the prognostic value of multiparametric CMR-derived imaging markers in patients with ischemic heart disease who underwent clinically indicated CMR examinations. Imaging parameters of interest include late gadolinium enhancement (LGE), infarct size, microvascular obstruction (MVO), left ventricular and left atrial strain, and native T1 and T2 mapping values. Long-term clinical outcomes will be obtained from existing medical records. The primary outcome is major adverse cardiovascular and cerebrovascular events (MACCE), and secondary outcome is cardiovascular death. This study seeks to clarify the role of CMR in long-term risk stratification of patients with ischemic heart disease.
CONDITIONS
Official Title
CMR Prognostic Markers in Ischemic Heart Disease
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Adults (≥18 years of age)
- Diagnosis of ischemic heart disease, including prior or recent myocardial infarction
- Underwent clinically indicated cardiac magnetic resonance imaging (CMR)
- Availability of analyzable CMR images including cine imaging, late gadolinium enhancement, and parametric mapping sequences
- Availability of baseline clinical data and longitudinal follow-up information
You will not qualify if you...
- Poor image quality or incomplete CMR data preventing quantitative analysis
- Presence of severe comorbid conditions expected to significantly affect survival or clinical outcomes
- Missing critical clinical outcome data during follow-up
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Fuwai Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College
Beijing, Beijing Municipality, China, 100037
Actively Recruiting
Research Team
Z
Zhaoxin Tian
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
1
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