Actively Recruiting
Prognostic Value of Multiparametric Cardiovascular Magnetic Resonance in Patients With Ischemic Heart Disease: A Multicenter Retrospective Cohort Study
Led by Chinese Academy of Medical Sciences, Fuwai Hospital · Updated on 2026-01-20
1000
Participants Needed
1
Research Sites
N/A
Total Duration
On this page
Sponsors
C
Chinese Academy of Medical Sciences, Fuwai Hospital
Lead Sponsor
N
National Natural Science Foundation of China
Collaborating Sponsor
AI-Summary
What this Trial Is About
Ischemic heart disease (IHD) is a major cause of illness and death worldwide, making accurate risk assessment crucial for better patient care and outcomes. This research investigates how detailed heart imaging using cardiovascular magnetic resonance (CMR) can help predict long-term risks in patients with ischemic heart conditions. The study uses existing clinical and imaging data from multiple centers to explore the value of various imaging markers in assessing heart damage and function. The study focuses on analyzing CMR images taken during routine clinical care. Key imaging features examined include late gadolinium enhancement (LGE) to detect heart tissue scarring, infarct size, microvascular obstruction (MVO), strain measurements of the heart's left chambers, and T1 and T2 mapping values. Data from these images, along with patient demographics, risk factors, treatments, and follow-up information, will be studied to understand their relationship with major cardiovascular events and death. Participants' medical records will be reviewed retrospectively to collect long-term outcomes, including major adverse cardiovascular and cerebrovascular events (MACCE) and cardiovascular death, over up to 10 years after their CMR exam. This observational study does not involve new treatments but analyzes existing data to improve risk prediction. The findings aim to help personalize patient care by clarifying how CMR imaging can guide long-term management of ischemic heart disease.
CONDITIONS
Brief Title
CMR Prognostic Markers in Ischemic Heart Disease
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Adults (18 years of age or older)
- Patients diagnosed with ischemic heart disease, including prior or recent myocardial infarction
- Underwent clinically indicated cardiac magnetic resonance (CMR) imaging
- Availability of analyzable CMR images such as cine imaging, late gadolinium enhancement (LGE), and parametric mapping sequences
- Availability of baseline clinical data and long-term follow-up information
You will not qualify if you...
- Poor image quality or incomplete CMR data preventing quantitative analysis
- Presence of severe other medical conditions expected to greatly affect survival or clinical outcomes
- Missing key clinical outcome data during follow-up
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Your Study Journey
Duration - 2 to 4 weeks
Participants are screened for eligibility to participate in the trial.
1 visit (in-person)
Duration - Single timepoint
Participants undergo cardiac magnetic resonance imaging as part of routine clinical care. Imaging data are used for observational research analyses without altering clinical management.
1 visit (in-person)
Duration - Up to 10 years
Participants are observed over time through retrospective collection of clinical and follow-up data to evaluate cardiovascular outcomes.
Follow-up visits as part of routine clinical care
Trial Site Locations
Total: 1 location
1
Fuwai Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College
Beijing, Beijing Municipality, China, 100037
Actively Recruiting
Research Team
Z
Zhaoxin Tian
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
1
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