Actively Recruiting

Age: 18Years +
All Genders
NCT04761991

CMR Versus CT in Coronary Artery Disease

Led by University of Leicester · Updated on 2025-07-01

300

Participants Needed

1

Research Sites

264 weeks

Total Duration

On this page

Sponsors

U

University of Leicester

Lead Sponsor

H

HeartFlow, Inc.

Collaborating Sponsor

AI-Summary

What this Trial Is About

CONCORD is a prospective observational study evaluating the diagnostic accuracy of cardiovascular magnetic resonance (CMR) and computed tomography with fractional flow reserve (CT-FFR) in patients with suspected coronary artery disease, using invasive fractional flow reserve (FFR) as the reference standard.

CONDITIONS

Official Title

CMR Versus CT in Coronary Artery Disease

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Patients aged 6518 years
  • Referred for invasive coronary angiography for investigation of chest pain
Not Eligible

You will not qualify if you...

  • Recent acute coronary syndrome (less than 6 months)
  • Previous coronary artery bypass grafting
  • Severe claustrophobia
  • Absolute contraindications to CMR (patients with MR conditional or safe devices will be included)
  • Second- or third-degree atrioventricular block
  • Severe chronic obstructive pulmonary disease
  • Moderate to severe asthma
  • Estimated glomerular filtration rate less than 30 ml/min/1.73m2
  • Women who are pregnant, breast-feeding, or of child-bearing potential (premenopausal women)
  • Contraindication to iodinated contrast
  • Participation in another research study involving an investigational product within the past 12 weeks

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Glenfield Hospital

Leicester, Leics, United Kingdom, LE3 (QP

Actively Recruiting

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Research Team

J

Jayanth Arnold

CONTACT

M

Mo Elshibly

CONTACT

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

0

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CMR Versus CT in Coronary Artery Disease | DecenTrialz