Actively Recruiting

Age: 18Years +
All Genders
Healthy Volunteers
NCT06164028

COA-APTIC Cognitive Interview Study of Caregiver and Clinician Assessment of Acute Pain in Infants and Young Children

Led by Duke University · Updated on 2025-09-09

60

Participants Needed

1

Research Sites

158 weeks

Total Duration

On this page

Sponsors

D

Duke University

Lead Sponsor

F

Food and Drug Administration (FDA)

Collaborating Sponsor

AI-Summary

What this Trial Is About

Evaluate the content validity and comprehensibility of a caregiver observer-reported outcome assessment and clinician-reported assessments for acute pain in children aged 0 to \<2 years. The primary objective of the Qualitative Protocol in the UH3 phase study is to establish or create reliable Clinical Outcome Assessments (COAs) and endpoints that can assess acute pain during clinical trials of pain therapeutics specifically designed for infants and young children (0 - \<2 years).

CONDITIONS

Official Title

COA-APTIC Cognitive Interview Study of Caregiver and Clinician Assessment of Acute Pain in Infants and Young Children

Who Can Participate

Age: 18Years +
All Genders
Healthy Volunteers

Eligibility Criteria

Eligible

You may qualify if you...

  • Caregiver of a child between 0 and less than 2 years old who is experiencing or has experienced acute pain in the past four weeks from malignant or non-malignant visceral or hematologic disease, surgery or other procedure, trauma or injury, or congenital conditions
  • Over 18 years old
  • Able to speak and understand English or Spanish
  • Willing and able to provide informed consent and allow medical record review
  • Clinician currently practicing in a clinical care environment
  • Treats pediatric patients aged 0 to less than 2 years for acute pain
  • Spends more than 50% of clinical time caring for pediatric patients
  • Holds a position as a physician, clinical pharmacist (Pharm D), nurse practitioner, physician assistant, or nurse (BSN/RN or higher)
  • Able to speak and understand English
  • Willing and able to provide informed consent for interview participation
Not Eligible

You will not qualify if you...

  • Lack of access to a telephone or computer for interview participation
  • For caregivers, child is premature at less than 32 weeks corrected gestational age at enrollment with no other eligible child

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Duke Clinical Research Institute

Durham, North Carolina, United States, 27701

Actively Recruiting

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Research Team

S

Sophie Wang, MBBS, MHS

CONTACT

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

2

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