Actively Recruiting
COCONUT Study Concomitant PVI and LAAC
Led by Asklepios proresearch · Updated on 2026-03-19
60
Participants Needed
1
Research Sites
91 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
In patients with non-valvular AF, at high stroke risk, and who are ineligible for long-term oral anticoagulation LAAC could be an alternative to anticoagulation and safety and efficacy has been shown in several studies and registries.8 While PVI and LAAC are both conducted in the left atrium and share the same access route, a combined concomitant approach might be beneficial for patients but is not conventionally practiced. Due to significantly shorter procedures times and high safety profile PFA based catheter ablation may be advantageous for the combined approach of PVI and LAAC. We are performing a word-wide, retrospective, multicenter registry study focusing on patients with concomitant Farapulse PFA based PVI and LAAC (WATCHMAN Flx, Boston Scientific). To evaluate safety, efficacy and efficiency in a multicenter study the COCONUT study was conducted.
CONDITIONS
Official Title
COCONUT Study Concomitant PVI and LAAC
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Indication for pulmonary vein isolation (PVI) and left atrial appendage closure (LAAC)
You will not qualify if you...
- Not eligible for either pulmonary vein isolation (PVI) or left atrial appendage closure (LAAC)
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Asklepios Klinik Altona
Hamburg, Free and Hanseatic City of Hamburg, Germany
Actively Recruiting
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
1
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