Actively Recruiting

Phase Not Applicable
Age: 18Years +
All Genders
NCT06490237

Coding of Speech Signals in the Human Auditory Nerve

Led by CHU de Reims · Updated on 2024-07-08

60

Participants Needed

1

Research Sites

286 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

The fine evaluation of the function of auditory neurons in silence and in noise in humans is difficult, if not impossible, to date with the conventional methods available. That is why in certain situations, the hearing aids of patient with hearing loss fail, especially in the presence of noise. In this study the investigators aim at investigating the global spontaneous and sound evoked human auditory nerve activity from electrophysiological acquisitions performed directly on the cochlear nerve in patients requiring posterior fossa surgery.

CONDITIONS

Official Title

Coding of Speech Signals in the Human Auditory Nerve

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Male or female over 18 years of age
  • Scheduled for surgery on the cerebellopontine angle (microvascular decompression, vestibular neurotomy, meningioma or schwannoma removal)
  • Mild to severe sensorineural hearing loss (average hearing loss > 20 dB and < 90 dB in bone conduction audiometry) on the operated ear side, OR normal hearing defined by average hearing thresholds ≤ 20 dB on the operated ear side
  • Affiliated with a social security system
  • Have read the study information and agreed in writing to participate by signing informed consent
Not Eligible

You will not qualify if you...

  • Auditory nerve not accessible during surgery due to complete tumor invasion of the cochlear nerve (stage III and IV neuroma, advanced meningioma)
  • Auditory nerve exposure impossible due to anatomical features not identified preoperatively (e.g., protrusion of the posterior face of the rock)

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Damien JOLLY

Reims, France

Actively Recruiting

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Research Team

X

Xavier DUBERNARD

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

NON_RANDOMIZED

Model

PARALLEL

Primary Purpose

BASIC_SCIENCE

Number of Arms

2

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