Actively Recruiting

Phase 1
Age: 5Years - 14Years
All Genders
Healthy Volunteers
NCT06342258

COES: Curing Order Effects on Sealants

Led by University of Southern California · Updated on 2025-05-31

217

Participants Needed

1

Research Sites

122 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

Background: Sealants are a great tool in the prevention of caries in the pediatric population. It has been shown that up to 71% of occlusal decay is preventable after a single sealant application in a fissure, and thus is the standard of care due to difficulty for pediatric patients in hygiene, diet, and overall home care until manual dexterity increases. Purpose: This prospective randomized case control study aims to look at the longevity of sealants with bonding agent cured prior to sealant placement vs those with uncured bond. The study will be performed by USC graduate pediatric personnel. Methods: A split mouth prospective randomized control study will be performed on pediatric dental patients at Long Beach Memorial's Children's Dental Health Clinic and USC Pediatric Dental Clinic, placing sealants with cured bond on half of a mouth and sealants with uncured bond on the contralateral half. Intraoral photos will be obtained at the initial visit and recalls to evaluate the overall retention/longevity of the sealant placement. The goal of this study is determine which sealant has higher longevity and to provide recommendations for future pediatric dentists regarding sealant procedures.

CONDITIONS

Official Title

COES: Curing Order Effects on Sealants

Who Can Participate

Age: 5Years - 14Years
All Genders
Healthy Volunteers

Eligibility Criteria

Eligible

You may qualify if you...

  • Children aged 5 to 14 years with ASA I or ASA II health status
  • Patients of CDHC and USC with adequately erupted permanent first or second molars
  • Teeth without previous restorations, interproximal lesions, pathology, or occlusal lesions
  • Child behavior rated as "positive" or "definitely positive" (Frankl 3 or 4)
  • Presence of contralateral molars in the same arch for sealant placement
Not Eligible

You will not qualify if you...

  • Any tooth with previous sealant placement
  • Allergy or intolerance to sealant material
  • Inability to tolerate dental suction isolation system
  • Failure to complete prophy cup polish
  • Presence of banded or bracketed molars
  • Inability of patient or parents to understand English or Spanish consent/assent form

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Herman Ostrow School of Dentistry of USC

Los Angeles, California, United States, 90089

Actively Recruiting

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Research Team

C

Catherine Pham, DDS

CONTACT

G

Grace Kim, DDS

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

DOUBLE

Allocation

RANDOMIZED

Model

CROSSOVER

Primary Purpose

TREATMENT

Number of Arms

2

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