Actively Recruiting

Phase Not Applicable
Age: 18Years +
All Genders
Healthy Volunteers
NCT07229443

CoGENES Randomized Controlled Trial (RCT)

Led by University of Southern California · Updated on 2026-05-12

140

Participants Needed

1

Research Sites

156 weeks

Total Duration

On this page

Sponsors

U

University of Southern California

Lead Sponsor

N

National Cancer Institute (NCI)

Collaborating Sponsor

AI-Summary

What this Trial Is About

This clinical trial evaluates the effectiveness of trained community engagement specialists for improving communication on colorectal cancer (CRC) prevention and genetic testing among Hispanic/Latino/a/x (H/L) communities. CRC is the second and third leading cause of cancer deaths among United States (US) H/L men and women respectively. Knowledge of inherited germline mutations (changes in a gene that occurs in a sperm or egg cell) is critical for understanding cause of disease and can impact patient treatment options and outcomes. Educational programs and participant engagement approaches focused on H/L individuals considering Latino cultural values, literacy, numeracy, barriers faced, cultural beliefs and attitudes, as well as language of participants are much needed to address these observed disparities. The Community Genetic Navigation Specialists (CoGENES) Program focuses on increasing knowledge, and preparing the CoGENES trainees to help respond to questions, fears, and concerns regarding genetic testing, counseling, biospecimen (sample of urine, blood, or tissue cells) donation and participation in clinical trials to H/L community members, patients and their families. CoGENES may improve communication on colorectal cancer prevention and genetic testing which can help reduce cancer disparities among H/L communities.

CONDITIONS

Official Title

CoGENES Randomized Controlled Trial (RCT)

Who Can Participate

Age: 18Years +
All Genders
Healthy Volunteers

Eligibility Criteria

Eligible

You may qualify if you...

  • Must be 18 years of age or older
  • Ability to understand and willingness to sign a written informed consent
  • Self-reported Hispanic/Latino/a/x ethnicity, of any race
  • Ability to read, write, and speak Spanish or English
  • Resides in Los Angeles County
Not Eligible

You will not qualify if you...

  • Younger than 18 years of age
  • Major cognitive deficit or psychiatric impairment
  • Unable to read and write Spanish or English
  • Resides outside of Los Angeles County
  • Community health educator or received colorectal cancer or cancer genetics training in the past three years

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

USC / Norris Comprehensive Cancer Center

Los Angeles, California, United States, 90033

Actively Recruiting

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Research Team

B

Bianca Rosales

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

HEALTH_SERVICES_RESEARCH

Number of Arms

2

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CoGENES Randomized Controlled Trial (RCT) | DecenTrialz