Actively Recruiting

Phase Not Applicable
Age: 40Years +
All Genders
ID06227572

Cognition After Obstructive Sleep Apnea Treatment Among Native American People (CATNAP)

Led by Washington State University · Updated on 2026-01-09

140

Participants Needed

1

Research Sites

N/A

Total Duration

On this page

Sponsors

W

Washington State University

Lead Sponsor

M

Missouri Breaks Industries Research, Inc.

Collaborating Sponsor

AI-Summary

What this Trial Is About

Researchers are evaluating a culturally informed motivational interviewing and electronic messaging intervention called CATNAP to support American Indian elders with obstructive sleep apnea (OSA) and prescribed positive airway pressure (PAP) therapy. This 9-month study focuses on improving PAP adherence and exploring the link between OSA and cognitive changes, including the risk of Alzheimer's disease and related dementias (ADRD). The trial includes 300 American Indian elders aged 50 years and older from Northern Plains Reservations and nearby communities. Participants will be randomized to either usual care or an intervention group receiving the CATNAP motivational interviewing sessions alongside electronic messages to encourage PAP use. The intervention involves three motivational interviewing sessions to increase knowledge about OSA, sleep health, and PAP adherence, plus personalized electronic messages. Usual care includes mask fitting, PAP machine training, and follow-up for adherence support. Data collection occurs at baseline, 3 months, and 9 months. During the study, researchers will monitor PAP use automatically via cloud uploads provided by Missouri Breaks Durable Medical Equipment. Outcomes measured include PAP adherence minutes and nights of use, plus cognitive function assessed by the Montreal Cognitive Assessment and Cognivue tests. The study aims to understand PAP adherence patterns and cognitive outcomes while assessing intervention impacts over the 9-month period.

CONDITIONS

Brief Title

Cognition After OSA Treatment Among Native American People (CATNAP)

Who Can Participate

Age: 40Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Age 50 years and older
  • Self-identify as American Indian or Alaskan Native
  • Diagnosed with obstructive sleep apnea
  • Prescribed positive airway pressure (PAP) therapy and have a PAP device
  • Ability to understand written and spoken English
  • Ability and willingness to follow all study protocols
Not Eligible

You will not qualify if you...

  • Living in a household with someone already enrolled in the study
  • Already using PAP device at Medicaid recommended standards
  • Cognitive decline preventing ability to consent independently

AI-Screening

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Your Study Journey

Screening

Duration - 2 to 4 weeks

Participants are screened for eligibility to participate in the trial.

1 visit (in-person)

Treatment

Duration - 9 months

Participants receive positive airway pressure (PAP) therapy. Those in the intervention group also participate in three motivational interviewing sessions and receive electronic messaging to support PAP adherence.

3 visits (baseline, 3 months, and 9 months)

Trial Site Locations

Total: 1 location

1

Missouri Breaks Industries Research Inc

Eagle Butte, South Dakota, United States, 57625

Actively Recruiting

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Research Team

D

Denise Dillard, PhD

M

Madison B Ramos, BA

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

TREATMENT

Number of Arms

2

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