Actively Recruiting
Cognition and Behavior With Sham Accelerated TMS
Led by University of California, Davis · Updated on 2026-05-06
25
Participants Needed
1
Research Sites
90 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
The goal of this clinical study is to understand how a person's expectations about treatment can influence their mood, motivation, and reactions to everyday rewards. The study includes young people ages 15-25 who will complete a sham (placebo) version of an accelerated transcranial magnetic stimulation (TMS) treatment. No active brain stimulation is given. The main questions this study aims to answer are: 1. Do expectancy and treatment beliefs change during and after an accelerated sham TMS schedule? 2. Do these expectations influence mood, reward processing, or craving? 3. Does a more intensive schedule of sham sessions lead to different expectancy effects than a slower, once-daily schedule? Participants will: * Complete baseline clinical assessments and an MRI session * Undergo five days of accelerated sham TMS (no active brain stimulation is delivered) * Complete post-treatment MRI and follow-up assessments at 1 week and 4 weeks
CONDITIONS
Official Title
Cognition and Behavior With Sham Accelerated TMS
Who Can Participate
Eligibility Criteria
You may qualify if you...
- English speaking
- Able to provide informed consent (and assent if < 18 years)
- 15-25 years old
You will not qualify if you...
- Unable to consent due to medical condition, psychosis, substance use, etc
- Acute suicidal crisis or active medical illness interfering with participation
- Contraindications to MRI such as metal in the body, surgical clips, metal fragments in eyes, non-removable piercings, braces, or permanent retainers
- Major neurological problems including seizure disorder, traumatic brain injury with loss of consciousness, or sensory impairments like blindness
- Participation in any clinical study involving investigational treatment within previous 30 days or plans for concurrent participation
AI-Screening
AI-Powered Screening
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Trial Site Locations
Total: 1 location
1
UC Davis Medical Center
Sacramento, California, United States, 95817
Actively Recruiting
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
NA
Model
SINGLE_GROUP
Primary Purpose
BASIC_SCIENCE
Number of Arms
1
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