Actively Recruiting
Cognition and QoL After Thyroid Surgery
Led by Karolinska University Hospital · Updated on 2023-01-18
320
Participants Needed
1
Research Sites
197 weeks
Total Duration
On this page
Sponsors
K
Karolinska University Hospital
Lead Sponsor
T
The Netherlands Cancer Institute
Collaborating Sponsor
AI-Summary
What this Trial Is About
The development of cognitive dysfunction can profoundly affect HR-QoL as well as the possibility of societal participation and ability to work, and thereby relevantly impacts prospects for cancer survivorship. The aim of the study is to obtain improved understanding of the scope and magnitude of objective cognitive dysfunction in DTC survivors, and its relation to subjective cognitive dysfunction, thyroid hormone levels, physical activity and HRQoL. This is done in a prospective study where patients operated for a thyroid nodule (Bethesda IV-VI, i.e., benign \[goitre with nodule and fibroadenomas\], low-risk DTC and intermediate-high risk DTC) are included and asked to serially perform online neuropsychological testing as well as to complete questionnaires related to HR-QoL, physical activity and additional psychological and physical complaints. Blood is analysed for levels of thyroid hormones and systemic inflammation.
CONDITIONS
Official Title
Cognition and QoL After Thyroid Surgery
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Age over 18 years
- Indication for surgery due to a thyroid nodule classified as Bethesda IV-VI
- Ability to read and understand Swedish
- Access to a desktop or laptop computer with internet connection
- Willing and able to give written informed consent
You will not qualify if you...
- Previous diagnosis of autoimmune hypothyroidism
- Previous cancer diagnosis except basal cell skin cancer
- Surgery indication other than only a thyroid nodule (such as Graves disease)
- Diagnosis of medullary or anaplastic thyroid cancer
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Medical Unit Breast-, Endocrine tumors and Sarcoma
Stockholm, Sweden, 17176
Actively Recruiting
Research Team
R
Renske Altena, MD PhD
CONTACT
C
Cia Ihre Lundgren, MD Ass Professor
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
0
Not the Right Trial for You?
Explore thousands of other clinical trials that might be a better match.
Sign up to get personalized trial recommendations delivered to your inbox.
Already have an account? Log in here