Study of Cognitive Function and Quality of Life After Surgery for Benign and Malignant Thyroid Nodules

What this Trial Is About

Researchers are studying cognitive function and quality of life in people who have surgery for thyroid nodules. The study aims to understand the extent of objective cognitive problems and how they relate to subjective cognitive complaints, thyroid hormone levels, physical activity, and health-related quality of life. This prospective study includes patients with benign thyroid nodules, low-risk differentiated thyroid cancer, and intermediate to high-risk thyroid cancer. Participants are divided into three groups those with follicular adenomas, those with very low-risk thyroid cancer, and those with low to high-risk thyroid cancer. The main comparison focuses on patients with follicular adenomas and those with higher-risk thyroid cancer. Cognitive function is assessed using an online neuropsychological test called the Amsterdam Cognition Scale ACS. Participants complete online cognitive tests and questionnaires about quality of life, physical activity, and other psychological and physical symptoms at multiple times from before surgery up to 12 months after surgery. Blood samples are taken to measure thyroid hormone levels and signs of inflammation. The study measures objective cognitive function over time to better understand its impact on survivors of thyroid conditions.

Cognition and QoL After Thyroid Surgery