Actively Recruiting
Cognitive Assessment Tools for Huntington's Disease.
Led by Ohio State University · Updated on 2026-03-02
76
Participants Needed
1
Research Sites
127 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
The purpose of the current proposal is to expand understanding of two currently available cognitive tools that are not typically used in Huntington Disease (HD) clinical trials that might be useful both for initial screening and for clinical trial application. One is the Coding Test and the other is the Self-Administered Gerocognitive Examination (SAGE). Both the Coding Test and the SAGE have been used for assessments of individuals with other neurodegenerative diseases, including Alzheimer's Disease, Parkinson's Disease and Lewy Body Disease, but data is lacking on their use in individuals with HD.
CONDITIONS
Official Title
Cognitive Assessment Tools for Huntington's Disease.
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Males and females aged 30-65 (inclusive) at the time of signing the informed consent form
- Genetic diagnosis of HD with a CAG repeat size of 40 or more
- Clinical diagnosis of HD with a Diagnostic Confidence Level of 4
- Vision and hearing sufficient to comply with tests
- On a stable dose of medications for at least 30 days prior to consent
You will not qualify if you...
- Symptom onset age less than 19 or greater than 60 years old
- Serious neurological disorders aside from HD (e.g., Alzheimer's, Parkinson's, Frontotemporal dementia, Lewy body dementia, ALS, Traumatic Brain Injury) considered clinically significant
- Serious ongoing medical conditions considered clinically significant (e.g., autoimmune diseases, cancer treatment, congestive heart failure, severe pulmonary disease, seizure disorder requiring anti-epileptics)
- Pregnant or breastfeeding
- History of a learning disability
- Unable to provide consent
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
The Ohio State University Wexner Medical Center
Columbus, Ohio, United States, 43221
Actively Recruiting
Research Team
N
Nicole E Vrettos
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
1
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