Actively Recruiting

Phase Not Applicable
Age: 65Years +
All Genders
Healthy Volunteers
NCT06631781

Cognitive Control Mechanisms in Older Adults

Led by Hebrew University of Jerusalem · Updated on 2024-10-08

42

Participants Needed

1

Research Sites

82 weeks

Total Duration

On this page

Sponsors

H

Hebrew University of Jerusalem

Lead Sponsor

U

University of Melbourne

Collaborating Sponsor

AI-Summary

What this Trial Is About

The prevalence of depressive symptoms in older adults is on the rise, affecting 13 to 37% of older adults globally. These symptoms significantly impact health, increasing the risk of dementia and cognitive decline, and impairing daily functioning and quality of life. Reduced cognitive control (CC) is a key factor contributing to depressive symptoms, affecting 40% of adults with such symptoms. Despite this, over half of affected adults do not respond well to available treatments. Computerized cognitive training (CCT) has shown efficacy in improving CC but its impact on daily functioning is limited. The Cognitive Orientation to Occupational Performance (CO-OP) approach has demonstrated promise in improving daily functioning, as measured by occupational performance (OP). We propose a novel intervention, GOLD-Cog+, combining CCT and CO-OP, to address CC and functional deficits in older adults with depressive symptoms.

CONDITIONS

Official Title

Cognitive Control Mechanisms in Older Adults

Who Can Participate

Age: 65Years +
All Genders
Healthy Volunteers

Eligibility Criteria

Eligible

You may qualify if you...

  • Depressive symptoms with Patient Health Questionnaire (PHQ-8) score of 5 or higher
  • Healthy cognition with Montreal Cognitive Assessment (MoCa) score of 20 or higher
  • Able to sign and agree to participate in the study
  • Basic technological skills to use a tablet based on self-report
  • Adequate sight and hearing (with assistive technology if needed) to use a tablet and participate in a small group
  • Able to fluently read, speak, and understand Hebrew or English
Not Eligible

You will not qualify if you...

  • Any neurodegenerative disorder such as Mild Cognitive Impairment, Dementia, or Parkinson's disease (self-reported)
  • Psychiatric disorders other than depression or anxiety, including Schizophrenia, Bipolar, or Psychotic disorders (self-reported)

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Computerized Neurotherapy Lab, School of OT, Hebrew University, Mt. Scopus Campus

Jerusalem, Israel

Actively Recruiting

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Research Team

E

Eliane Gefen, MsC

CONTACT

M

Mor Nahum, Professor

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

RANDOMIZED

Model

CROSSOVER

Primary Purpose

TREATMENT

Number of Arms

2

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Cognitive Control Mechanisms in Older Adults | DecenTrialz