Actively Recruiting
Cognitive Decline and Underlying Mechanisms in Symptomatic Intracranial Artery Stenosis Patients: A Cohort Study
Led by Anhui Medical University · Updated on 2025-11-17
100
Participants Needed
1
Research Sites
217 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
The purpose of this study is to explore the mechanism of cognitive impairment in patients with symptomatic intracranial atherosclerotic stenosis (ICAS), and further plans to explore the impact of different treatment options on cognitive function in symptomatic ICAS patients.
CONDITIONS
Official Title
Cognitive Decline and Underlying Mechanisms in Symptomatic Intracranial Artery Stenosis Patients: A Cohort Study
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Age between 18 and 80 years
- Severe stenosis (70%-99%) of atherosclerotic internal carotid artery (C6 or C7 segment) or middle cerebral artery (M1 segment) confirmed by angiography or at least two non-invasive imaging exams
- History of transient ischemic attack (TIA) or minor stroke with NIH Stroke Scale score of 4 or less
- Right-handed and able to cooperate with neuropsychological tests
- At least 14 days after onset of cerebral infarction or TIA
- Provided signed informed consent
You will not qualify if you...
- Other diseases affecting cognitive function such as cerebral hemorrhage, Parkinson's disease, neurosyphilis, dementia, tumors
- Right upper limb paralysis, aphasia, visual field defects, or visual impairments
- More than 50% stenosis of extracranial internal carotid artery, vertebral artery, or basilar artery
- Vasculitis, moyamoya disease, or cardiogenic stroke
- Previous head and neck stent implantation, carotid endarterectomy, aneurysm embolization, or other intracranial surgeries
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Anhui Medical University
Hefei, Anhui, China, 230032
Actively Recruiting
Research Team
K
Kai Wang, PhD
CONTACT
Q
Qiang Wei, PhD
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
2
Not the Right Trial for You?
Explore thousands of other clinical trials that might be a better match.
Sign up to get personalized trial recommendations delivered to your inbox.
Already have an account? Log in here