Actively Recruiting

Phase Not Applicable
Age: 18Years - 60Years
All Genders
NCT05954182

Cognitive Enhancement Intervention for Creating a Healthy L.I.F.E (Lifestyle Interventions for Epilepsy)

Led by Kayela Arrotta · Updated on 2025-07-03

170

Participants Needed

1

Research Sites

140 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

The goal of this clinical trial is to test if cognitive interventions in those with diagnosed epilepsy can help lessen cognitive lapses and improve overall brain health. Participants will participate in weekly, virtual group sessions led by a neuropsychologist for 12 weeks. After the 12-week mark, participants will be asked to practice what they learned for 9 more months. Participants will be asked to complete online questionnaires at certain times during the study. Researchers will compare this intervention group to another group that did not get the intervention to see if the intervention improves brain health. Participation in each of these groups will be randomly assigned. Participation in the study will last for one year.

CONDITIONS

Official Title

Cognitive Enhancement Intervention for Creating a Healthy L.I.F.E (Lifestyle Interventions for Epilepsy)

Who Can Participate

Age: 18Years - 60Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Adults aged 18 to 60 years with diagnosed epilepsy
  • Subjective cognitive difficulties or objective cognitive deficits
  • Able to provide informed consent independently
  • Fluent in English
  • Reading skills at or above 8th grade level
  • Access to internet and ability to participate in online video streaming
  • No history of epilepsy surgery
  • Willing and able to take part in cognitive intervention
Not Eligible

You will not qualify if you...

  • Diagnosis of non-epileptic or psychogenic seizures
  • Cognitive rehabilitation/intervention within last 6 months
  • Enrolled in another interventional epilepsy study at enrollment
  • Planned epilepsy surgery within 6 months
  • Pending litigation related to epilepsy cause unless for disability application
  • Undergoing intensive treatment for serious illness affecting participation
  • Serious psychiatric conditions interfering with participation
  • Currently pregnant or less than 6 weeks postpartum
  • Significant hearing or vision loss preventing remote testing or intervention
  • Requires legal authorized representative or lacks capacity to consent

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Cleveland Clinic

Cleveland, Ohio, United States, 44195

Actively Recruiting

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Research Team

A

Anthony Lioi, PhD

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

TREATMENT

Number of Arms

2

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Cognitive Enhancement Intervention for Creating a Healthy L.I.F.E (Lifestyle Interventions for Epilepsy) | DecenTrialz