Actively Recruiting

Phase Not Applicable
Age: 18Years +
All Genders
NCT07091344

Cognitive and Metacognitive Evaluation in VR-Based Avatar Therapy for Psychosis

Led by Fundació Sant Joan de Déu · Updated on 2025-08-29

30

Participants Needed

1

Research Sites

147 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

This study aims to evaluate the relationship between cognitive, metacognitive and social cognition variables in patients with psychosis undergoing VR-based Avatar Therapy for the treatment of auditory hallucinations. In addition to the primary intervention, participants will be assessed using validated tools for emotion recognition, attributional style, theory of mind, neurocognition, and metacognition. The study also explores the potential role of trauma as a predisposing factor. Assessments will be conducted at four time points: screening (week 0), baseline (week 12), intervention period (weeks 12-24), and post-therapy follow-up (week 24). By investigating these variables, this study seeks to better understand their impact on treatment outcomes and contribute to the development of personalized therapeutic approaches.

CONDITIONS

Official Title

Cognitive and Metacognitive Evaluation in VR-Based Avatar Therapy for Psychosis

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Adults aged 18 years or older
  • Diagnosis of schizophrenia spectrum disorder according to DSM-5 criteria
  • Persistent auditory hallucinations for at least 3 months with PANSS hallucination score 23 3
  • Stable medication dosage for at least 4 weeks prior to recruitment
  • Fluent in the spoken language of the study site (Spanish)
  • Able to provide informed consent
  • Regular psychiatric follow-up care
Not Eligible

You will not qualify if you...

  • Inability to identify a dominant voice for Avatar Therapy
  • Intellectual disability based on medical history
  • Active substance abuse
  • Central nervous system injury or neurological disorders affecting cognitive performance
  • Severe visual impairment preventing VR use
  • Aversion to virtual reality or prior simulator sickness
  • Current suicidal ideation or risk
  • Lack of cooperation or inability to comply with study procedures

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Fundació Sant Joan de Déu - Unitat de Recerca del Parc Sanitari Sant Joan de Déu

Barcelona, Catalonia, Spain, 08950

Actively Recruiting

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Research Team

S

Susana Ochoa, PhD

CONTACT

L

Luciana Díaz-Cutraro, PhD

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

NA

Model

SINGLE_GROUP

Primary Purpose

TREATMENT

Number of Arms

1

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