Actively Recruiting

Phase Not Applicable
Age: 60Years +
All Genders
NCT07356336

Cognitive Model for Behavioral Interventions as a Non-pharmacological Intervention for Behavioral and Psychological Symptoms of Dementia

Led by Vrije Universiteit Brussel · Updated on 2026-02-11

60

Participants Needed

1

Research Sites

149 weeks

Total Duration

On this page

Sponsors

V

Vrije Universiteit Brussel

Lead Sponsor

A

Alexianen Zorggroep Tienen

Collaborating Sponsor

AI-Summary

What this Trial Is About

The goal of this study is to evaluate whether the Cognitive Model for Behavioral Interventions (CoMBI), a person-centered, non-pharmacological intervention, can reduce behavioral and psychological symptoms of dementia (BPSD) in people with dementia living in nursing homes. The study also aims to examine whether CoMBI can reduce caregiver burden and improve quality of life in people with dementia. The main questions it aims to answer are: Does CoMBI reduce the severity of behavioral and psychological symptoms of dementia compared to care as usual? Does a reduction in BPSD lead to lower caregiver burden and improved quality of life for people with dementia? Do personal factors, such as personality (dys)functioning, gender, level of cognitive impairment and stage of dementia, influence the effectiveness of CoMBI? Researchers will compare CoMBI to care as usual to determine whether CoMBI leads to better outcomes for people with dementia and their caregivers. Participants will: Receive care in residential long-term care facilities where care staff are trained to apply CoMBI. Be observed and assessed repeatedly over time as part of a stepped-wedge cluster randomized trial design.

CONDITIONS

Official Title

Cognitive Model for Behavioral Interventions as a Non-pharmacological Intervention for Behavioral and Psychological Symptoms of Dementia

Who Can Participate

Age: 60Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Resident in a participating nursing home
  • Formal diagnosis of neurocognitive disorder (NCD) according to DSM-5-TR or medical record indicating probable dementia
  • Presence of one or more behavioral and psychological symptoms of dementia (BPSD) at study start measured by NPI-Q
  • Primary caregivers and patient's representative or close relative able to complete questionnaires in Dutch
  • Informant completing premorbid personality questionnaire knows the patient well before dementia onset
  • Informed consent obtained from resident or legal representative if resident is legally incapacitated
Not Eligible

You will not qualify if you...

  • Nursing homes already using a structured, theory-based behavioral counseling as care as usual

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

1
2
3
+1

Trial Site Locations

Total: 1 location

1

Alexianen Zorggroep Tienen

Tienen, Vlaams-Brabant, Belgium, 3300

Actively Recruiting

Loading map...

Research Team

J

Jessica Vandezande

CONTACT

G

Gina Rossi, Prof. Dr.

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

NA

Model

SINGLE_GROUP

Primary Purpose

TREATMENT

Number of Arms

2

Not the Right Trial for You?

Explore thousands of other clinical trials that might be a better match.
Sign up to get personalized trial recommendations delivered to your inbox.

Already have an account? Log in here