Actively Recruiting
Cognitive Processing Therapy (CPT) for Perinatal Posttraumatic Stress Disorder (PTSD)
Led by University of Texas at Austin · Updated on 2025-07-11
60
Participants Needed
1
Research Sites
74 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
Pregnant women with a primary diagnosis of posttraumatic stress disorder (PTSD) (PTSD Checklist for DSM-5 (PCL-5) score \> 33) will be randomized to receive conventional cognitive processing therapy (CPT) (60-min session once/week for 12 weeks) or massed CPT (mCPT) (an intensive schedule of 12 60-min sessions over 5 days, approximately 2-3 sessions per day) via telemedicine, for treatment of PTSD. The research aims will be three-fold: (1) Evaluate the relative efficacy and tolerability of CPT vs. mCPT for treatment of perinatal PTSD and depression; (2) Determine the effect of CPT upon maternal-infant attachment and interaction; (3) Collect pilot data of obstetric and neonatal outcomes among those receiving the two CPT delivery schedules.
CONDITIONS
Official Title
Cognitive Processing Therapy (CPT) for Perinatal Posttraumatic Stress Disorder (PTSD)
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Female, ages 18 to 46
- Pregnant less than 25 weeks
- Able to read and write in English
- History of at least 1 criterion A trauma
- Primary diagnosis of PTSD confirmed by SCID
- Psychotropic medications stable with no changes for at least 2 weeks (6 weeks for fluoxetine)
- No medication changes allowed during therapy
You will not qualify if you...
- Not currently pregnant
- Diagnosis of bipolar disorder
- Diagnosis of psychotic disorders
- Suicidal ideation with plan or intent
- Substance use disorder
- Regular benzodiazepine use more than 4 times weekly
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
University of Texas at Austin, Dell Medical School, Department of Psychiatry
Austin, Texas, United States, 78701
Actively Recruiting
Research Team
R
Research Associate I
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
2
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