Actively Recruiting

Phase Not Applicable
Age: 14Years - 21Years
All Genders
NCT06873841

Cognitive-psychophysiological Treatment for Tics in Young People With Tourette's Syndrome With or Without Biofeedback

Led by Université du Québec a Montréal · Updated on 2025-07-08

150

Participants Needed

1

Research Sites

241 weeks

Total Duration

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Sponsors

U

Université du Québec a Montréal

Lead Sponsor

C

Ciusss de L'Est de l'Île de Montréal

Collaborating Sponsor

AI-Summary

What this Trial Is About

The goal of this clinical trial is to compare the effectiveness of CoPs therapy with or without the therapeutic component of biofeedback in treating tics in Tourette Syndrome with emerging young adults. Hypotheses: 1. The CoPs+Biofeedback treatment will improve the severity of tics (YGTSS) and the Clinical Global Impression, surpassing the clinical significance threshold of CoPs treatment alone. 2. We expect that the identified variables (psychosocial, neurocognitive, biological) will predict the improvement of tics. Researchers will compare if the biofeedback treatment will improve the severity of tics. * In the pre-test, participants will undergo two interviews, each lasting 3 hours. These interviews will assess (through a battery of tests) the severity of tics as well as the psychosocial, biological, and neurocognitive aspects of functioning. A general assessment of intelligence and executive functions will also be conducted. * They will next attend 10 to 12 therapy sessions, with or without biofeedback. (The biofeedback component is explained in more detail in the ''Study Design'' section). * The post-test follow-ups consist of two evaluations: one 3 months after the end of the treatment and the other 6 months after. The evaluation will be done using the same battery of tests as during the pre-test interview.

CONDITIONS

Official Title

Cognitive-psychophysiological Treatment for Tics in Young People With Tourette's Syndrome With or Without Biofeedback

Who Can Participate

Age: 14Years - 21Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Have a diagnosis of Tourette Syndrome or experience bothersome tics
  • Be aged 14 to 21 years inclusive at the start of therapy
Not Eligible

You will not qualify if you...

  • Present a sensorimotor impairment
  • Have a diagnosis of intellectual disability (IQ below 75)
  • Alcohol or drug abuse
  • Have a neurological issue (e.g., hemifacial spasms, Huntington's disease)
  • Change medication one month or less before step 1 and up to step 4 without informing the research team
  • Receive another intervention for tics simultaneously without informing the research team

AI-Screening

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Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Centre intégré universitaire de santé et de services sociaux du Nord-de-l'Île-de-Montréal, Hôpital Rivières-des-Prairies

Montreal, Quebec, Canada, H1E 1A4

Actively Recruiting

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Research Team

J

Julie Leclerc, Psychology

CONTACT

A

Audrey-Ann Lachance

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

TRIPLE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

TREATMENT

Number of Arms

2

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