Exploring Cognitive Recovery: the Impact of Sensor-based Robotic Rehabilitation in Neurological and Neurodegenerative Disorders

What this Trial Is About

Researchers are evaluating whether sensor-based robotic upper limb rehabilitation combined with cognitive exercises can improve both cognitive and motor functions in adults with neurological and neurodegenerative disorders such as Parkinson's disease, multiple sclerosis, and stroke. The study aims to determine if this integrated approach leads to better improvements in attention, memory, executive functions, motor recovery, and daily activities compared to conventional therapy. The trial is a randomized controlled study designed to explore these outcomes in adults aged 18 to 75 years. Participants will be randomly assigned to one of two groups: an experimental group receiving upper limb rehabilitation using sensor-based robotic devices with virtual reality exercises and embedded cognitive tasks, and a control group receiving conventional physiotherapy focused on motor recovery without robotic assistance or cognitive training. Each participant will complete 25 training sessions lasting 60 minutes each, conducted 2 to 3 times per week over about 8 to 12 weeks. Therapy intensity and difficulty will be adjusted individually in the robotic group. During the study, participants will undergo neuropsychological assessments tailored to their condition and motor function tests before and after the intervention. These include tools like ACE-R, BRB-N, and RBANS for cognition, and Fugl-Meyer Assessment and Nine Hole Peg Test for motor skills. Researchers will measure changes in cognitive scores and motor function from baseline to the end of treatment. The study also evaluates the usability of the robotic devices and goal attainment, with safety and progress monitored throughout the trial's duration.

Cognitive Recovery Via Sensor-based Robotic Upper Limb Rehabilitation in Neurological Disorders