Actively Recruiting
Cognitive Rehabilitation of Deficits in Patients With Multiple Sclerosis: Proposal for an Integrated Cognitive Treatment in a Telematic Format
Led by Universita di Verona · Updated on 2025-05-09
60
Participants Needed
1
Research Sites
23 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
Researchers are evaluating cognitive rehabilitation methods for patients diagnosed with Multiple Sclerosis (MS), including relapsing-remitting, primary progressive, or secondary progressive types. The study aims to determine if a computer-based cognitive treatment delivered remotely through telerehabilitation is not less effective than the same treatment given in person. It also examines how these approaches affect attention, memory, executive functions, and daily living aspects such as cognitive fatigue, quality of life, and mood in people with MS. Participants receive three hours per week of cognitive rehabilitation using a computerized device tailored to their needs. One group completes the treatment independently at home via telerehabilitation, while the other attends in-person sessions where a therapist activates and guides the use of the device. This randomized, single-blind trial compares these two delivery methods over an eight-week treatment period. During the study, patients undergo several cognitive and functional tests before treatment, after eight weeks of therapy, and two months following treatment completion. These include assessments of attention, memory, executive function, fatigue, quality of life, and mood. Researchers use these measures to evaluate the effectiveness and long-term impact of the two rehabilitation approaches. The total participation duration includes treatment and follow-up assessments to monitor sustained benefits.
CONDITIONS
Brief Title
Cognitive Rehabilitation of Deficits in Patients With Multiple Sclerosis
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Diagnosis of relapsing-remitting, primary progressive, or secondary progressive multiple sclerosis for at least 3 to 6 months
- Age between 18 and 65 years
- Expanded Disability Status Scale (EDSS) score between 3 and 5 indicating mild to moderate neurological disability
- Presence of memory, attention, or executive function disorders confirmed by the Oxford Cognitive Screen
- Access to internet at home for telerehabilitation
- Adequate vision and hearing to use the rehabilitation device
You will not qualify if you...
- Other neurological conditions
- History of psychiatric disorders
- Alcohol or drug abuse
- Severe uncorrected visual impairments
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Your Study Journey
Duration - 2 to 4 weeks
Participants are screened for eligibility to participate in the trial.
1 visit (in-person)
Duration - 8 weeks
Participants receive cognitive rehabilitation treatment either remotely via telerehabilitation or in-person using a computerized device. Each treatment involves three hours of cognitive exercises per week tailored to individual needs.
Weekly visits for up to 8 weeks
Duration - 2 months
Participants are monitored two months after the end of treatment to assess cognitive function and quality of life.
1 follow-up visit (in-person)
Trial Site Locations
Total: 1 location
1
Azienda Ospedaliera Universitaria Integrata Verona - UOC di Neuroriabilitazione
Verona, verona, Italy, 37134
Actively Recruiting
Research Team
V
Valentina Varalta, Doctor
How is the study designed?
Study Type
INTERVENTIONAL
Masking
SINGLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
2
Similar Trials
Frequently Asked Questions
Have more questions? Get in touch with our team for quick support
Not the Right Trial for You?
Explore thousands of other clinical trials that might be a better match.
Sign up to get personalized trial recommendations delivered to your inbox.
Already have an account? Log in here