Actively Recruiting

Phase Not Applicable
Age: 18Years - 65Years
All Genders
NCT06964581

Cognitive Rehabilitation of Deficits in Patients With Multiple Sclerosis

Led by Universita di Verona · Updated on 2025-05-09

60

Participants Needed

1

Research Sites

137 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

Non-Inferiority Study, Post-Market Clinical Investigation with a Device, Single-Blind Randomized Controlled Trial in a Cohort of Patients Diagnosed with Multiple Sclerosis (MS). The aim of the study is to assess whether a computer-based cognitive treatment delivered via telerehabilitation produces effects from T0 to T1 that are not inferior to those of an in-person treatment on sustained attention in a cohort of patients with MS. The secondary objective is to evaluate the effects of telerehabilitation compared to the same treatment delivered in person on attentional shifting, memory, executive functions, and daily functioning (including cognitive fatigue, quality of life, and mood) in patients with MS.

CONDITIONS

Official Title

Cognitive Rehabilitation of Deficits in Patients With Multiple Sclerosis

Who Can Participate

Age: 18Years - 65Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Diagnosis of relapsing-remitting, primary progressive, or secondary progressive multiple sclerosis for at least 3-6 months
  • Age between 18 and 65 years
  • Expanded Disability Status Scale (EDSS) score between 3 and 5 indicating mild to moderate neurological disability
  • Presence of memory, attention, or executive function disorders confirmed by Oxford Cognitive Screen (OCS)
  • Availability of internet at home for telerehabilitation
  • Adequate visual and auditory abilities to use the rehabilitation device
Not Eligible

You will not qualify if you...

  • Other neurological conditions
  • History of psychiatric disorders
  • Alcohol or drug abuse
  • Severe visual deficits that are not corrected

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Azienda Ospedaliera Universitaria Integrata Verona - UOC di Neuroriabilitazione

Verona, verona, Italy, 37134

Actively Recruiting

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Research Team

V

Valentina Varalta, Doctor

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

SINGLE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

TREATMENT

Number of Arms

2

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