Actively Recruiting
Cognitive Rehabilitation Following Breast Cancer Treatment
Led by University of Missouri-Columbia · Updated on 2026-02-19
50
Participants Needed
1
Research Sites
86 weeks
Total Duration
On this page
Sponsors
U
University of Missouri-Columbia
Lead Sponsor
N
National Institutes of Health (NIH)
Collaborating Sponsor
AI-Summary
What this Trial Is About
The goal of this proposed project is to evaluate the feasibility and preliminary effect of metacognitive strategy training to improve activity performance, cognition, and quality of life in breast cancer survivors with cancer-related cognitive impairment (CRCI). The other goal of this proposed project is to examine the effects of CO-OP on resting (rsFC)- and task-state functional connectivity as compared to an inactive control group.
CONDITIONS
Official Title
Cognitive Rehabilitation Following Breast Cancer Treatment
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Self-reported moderate to extreme cancer-related cognitive impairment and Cognitive Failures Questionnaire score over 30
- Completed treatment for invasive ductal or lobular breast cancer (Stages I, II, or III) between 6 months and 3 years prior
- Able to read, write, and speak English fluently
- Able to provide valid informed consent
- Life expectancy greater than 6 months at enrollment
- On stable doses of medications affecting cognitive function with no changes in past 90 days
You will not qualify if you...
- Prior cancer diagnosis at other sites with active disease within the past year
- Active acute or chronic brain-related neurological conditions affecting brain structure or function, including Parkinson's disease or dementia
- Dementia symptoms indicated by a Montreal Cognitive Assessment score below 23
- Severe depressive symptoms with a PHQ-9 score of 21 or higher
- History of severe traumatic brain injury or prolonged loss of consciousness
- Conditions that prevent MRI scanning, such as electrical implants, pumps, or claustrophobia
- Blue-yellow colorblindness
- Pregnancy
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
University of Missouri
Columbia, Missouri, United States, 65211
Actively Recruiting
Research Team
A
Anna E. Boone, PhD, OTR/L
CONTACT
J
Juliana H. Earwood, OTD, OTR/L
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
SINGLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
2
Not the Right Trial for You?
Explore thousands of other clinical trials that might be a better match.
Sign up to get personalized trial recommendations delivered to your inbox.
Already have an account? Log in here