Actively Recruiting

Phase Not Applicable
Age: 18Years +
All Genders
NCT07316543

Cognitive Rehabilitation for Veterans With PNES

Led by VA Office of Research and Development · Updated on 2026-03-12

47

Participants Needed

1

Research Sites

278 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

Psychogenic nonepileptic seizures (PNES) reflect a subtype of functional neurological disorder (FND) that is common and extremely disabling in Veterans. Cognitive problems are highly prevalent in PNES, they reduce quality of life, and they severely limit daily functioning. Currently, there are no available treatments that target cognition to improve daily function in PNES or other FNDs, leaving a major gap in the literature. Cognitive re-habilitation improves daily functioning in Veterans with related neuropsychiatric disorders and has a high chance of success in Veterans with PNES. The proposed study will solicit direct input from Veterans with PNES via qualitative interviews to inform the design of a cognitive treatment workbook. The workbook will then be iteratively refined based on participatory feedback from Veterans with PNES and their treatment providers. The full cognitive intervention protocol will be pilot tested to inform a fully powered RCT. Results will support a line of research that aims to improve cognition and function in Veterans with PNES and related FNDs.

CONDITIONS

Official Title

Cognitive Rehabilitation for Veterans With PNES

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • U.S. Veteran
  • Able to provide informed consent
  • Reports cognitive difficulties
  • Prior video EEG diagnosis of PNES
  • English speaking
  • Able to read at least at 8th grade level
  • Access to a private space with a computer (13-inch monitor)
  • Internet access
Not Eligible

You will not qualify if you...

  • Acute psychosis (hallucinations or delusions)
  • Current active suicidality
  • Diagnosis of dementia or intellectual disability
  • Sensory impairment (e.g., deafness) that would preclude participation

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Providence VA Medical Center, Providence, RI

Providence, Rhode Island, United States, 02908-4734

Actively Recruiting

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Research Team

M

Madeleine R Lefkowitz, BS

CONTACT

A

Alison Gorbatov

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

NA

Model

SINGLE_GROUP

Primary Purpose

TREATMENT

Number of Arms

1

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