Actively Recruiting
Cognitive-Sensorimotor Function in Long-COVID
Led by VA Office of Research and Development · Updated on 2026-05-08
136
Participants Needed
1
Research Sites
247 weeks
Total Duration
On this page
Sponsors
V
VA Office of Research and Development
Lead Sponsor
E
Edward Hines Jr. VA Hospital
Collaborating Sponsor
AI-Summary
What this Trial Is About
Growing evidence indicates that many people who have chronic post-acute sequelae of SARS-CoV-2 infection (PASC) will experience ongoing neurological and musculoskeletal impairment that can affect gait and balance. Identifying the factors contributing to these impairments and how they influence functional mobility is the first step towards creating effective evaluation and treatment protocols. In this study the investigators will examine cognition, vision, proprioception, muscle strength, gait and balance in persons with and without PASC to understand how PASC may impact functional mobility through a cognitive-sensorimotor lens. Gait and balance will be studied in environments that stress cognitive and sensory abilities. Study outcomes will be critical for the development of evidence-based Veteran Health Administration diagnostic and standard-of-care protocols to address gait and balance dysfunction in Veterans with PASC for restoring their functional mobility and independence.
CONDITIONS
Official Title
Cognitive-Sensorimotor Function in Long-COVID
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Older than 18 years of age
- Positive PCR or Rapid COVID-19 test in the past
- Onset of COVID-19 illness greater than 3 months prior to their participation in the study
- Self-reported ability to walk 10 meters with or without external assistance prior to COVID-19 illness
You will not qualify if you...
- Severe cardiovascular and pulmonary disease and/or neurological and musculoskeletal disorders not related to COVID-19 (e.g., amputation, stroke, spinal cord injury)
- Cognitive impairments preventing ability to provide informed consent
- Severe acute COVID-19 infection requiring hospitalization or diagnosis of post-intensive care syndrome
- Musculoskeletal, inflammatory, or neurological conditions that mimic Long COVID symptoms (e.g., concussion in last 5 years, chronic fibromyalgia, myofascial pain syndrome)
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Jesse Brown VA Medical Center, Chicago, IL
Chicago, Illinois, United States, 60612
Actively Recruiting
Research Team
M
Matthew J Major, PhD
CONTACT
K
Keith E Gordon, PhD
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
2
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