Actively Recruiting
Evaluation of Cognitive Stimulation on Dysexecutive Residual Symptoms in Bipolar Patients Over 65 Years of Age
Led by Groupe Hospitalier de la Rochelle Ré Aunis · Updated on 2025-03-17
40
Participants Needed
1
Research Sites
26 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
Researchers are investigating a cognitive stimulation program adapted for elderly patients with bipolar disorder to address cognitive impairments that commonly worsen after age 65. Bipolar disorder is a mood disorder that significantly affects cognitive functions such as attention, memory, and executive skills, which in turn impact quality of life and relapse risk. This study compares the adapted cognitive stimulation program to usual psychiatric care to evaluate its effects on residual cognitive symptoms. Participants in the study will either undergo cognitive stimulation sessions using Liliane Israël's "TRAIN YOUR MEMORY" software or receive standard care involving psychiatric consultations and possible home nurse visits. The cognitive stimulation includes weekly sessions focusing on sensory stimulation, language and expression, attention, memory structuring, social communication, and temporal-spatial orientation. This program is designed to enhance memory mechanisms through pedagogical and psychotherapeutic methods. During the trial, participants will be assessed with various cognitive and functional tests at inclusion, 3 months, and 6 months to measure changes in executive function, memory, daily activities, and mood. Key outcomes include scores on the Frontal Assessment Battery and other neuropsychological tests. Researchers will monitor hospitalizations due to relapse and caregiver burden. The total participation duration is at least 6 months, with assessments conducted throughout this period to evaluate treatment effects and safety.
CONDITIONS
Brief Title
Cognitive Stimulation for Elderly Bipolar Patients
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Age over 65 years old
- Diagnosis of bipolar illness for more than 10 years
- Currently in a euthymic (stable) phase
- Understands and speaks French
- Provides free and informed consent
- Mild to moderate neuro-cognitive impairments (Montreal Cognitive Assessment score between 16 and less than 26)
You will not qualify if you...
- Illiteracy
- Participation in other therapeutic workshops (e.g., psycho-geriatric day hospital care)
- Persons deprived of liberty by judicial or administrative decision
- Persons under legal protection measures
- Unable to provide consent
- Not a member or beneficiary of a social security scheme
- Refusal to participate in the study
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Your Study Journey
Duration - 2 to 4 weeks
Participants are screened for eligibility to participate in the trial.
1 visit (in-person)
Duration - 12 weeks
Participants receive cognitive stimulation sessions once a week, focusing on sensory stimulation, attention, memory, language, and daily life skills to support cognitive function.
Weekly visits for up to 12 weeks
Duration - 3 months
Participants are assessed to evaluate cognitive and functional outcomes after completing the treatment program.
1 visit at 3 months after inclusion and 1 visit at 6 months after inclusion
Trial Site Locations
Total: 1 location
1
Groupe Hospitalier de la Rochelle Ré Aunis
La Rochelle, France
Actively Recruiting
Research Team
C
Caroline ALLIX-BEGUEC, Ph.D.
How is the study designed?
Study Type
INTERVENTIONAL
Masking
SINGLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
SUPPORTIVE_CARE
Number of Arms
2
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