Actively Recruiting

Age: 18Years +
All Genders
NCT03149705

Cohort of Ischemic STROKE Patients

Led by Hospices Civils de Lyon · Updated on 2020-08-12

300

Participants Needed

1

Research Sites

520 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

Ischemic stroke is the first cause of acquired disability of the adult, the second cause of dementia and the third cause of death in the industrialized countries, what constitutes à major public health issue. Stroke is characterized by a cerebral parenchymal lesion due to an ischemic mechanism (85% of the cases) or hemorrhagic mechanism (15%). For a long time, the only approved treatment was the intravenous thrombolysis (rt-PA). Recently, thrombectomy has proven its superiority in this pathology. Cohorts of patients with stroke are rare but can be very valuable by their clinical, laboratory and imaging well documented. They are the source of new hypotheses for research or interventions as well as the quality of care assessment tool. The main objective of this project is to identify new markers: biological and imaging, treatment response and prognosis after ischemic stroke. Secondary objectives of the HIBISCUS-STROKE cohort are to establish a clinical database, completed by biological samples and by imaging data that can be used in the following areas: * Descriptive epidemiology of ischemic stroke and cerebral reperfusion, * Pharmacoepidemiology and treatments observatory: safety, efficacy, indication of treatment in real life, costs * Assessment of the long-term effect of the treatment on the occurrence of disability, stroke recurrence and death, * Quality of life and personal, familial, professional and social consequences of stroke, * Research of new diagnostic and prognostic biomarkers, * Research projects.

CONDITIONS

Official Title

Cohort of Ischemic STROKE Patients

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Age greater than 18 years
  • Ischemic stroke confirmed by MRI
  • Presence of proximal arterial occlusion (internal carotid artery or M1 segment)
  • Eligible for thrombolysis and/or thrombectomy treatment
Not Eligible

You will not qualify if you...

  • Residing more than 50 km from Pierre Wertheimer Hospital (Lyon, France)
  • Unable to perform the first sample collection (H0)
  • Having progressive or uncontrolled cancer
  • Refusal to participate or to sign consent
  • Lack of medical social coverage
  • Deprivation of civil rights

AI-Screening

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Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Hôpital neurologique Pierre Wertheimer (Lyon)

Bron, France, 69500

Actively Recruiting

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Research Team

N

Norbert NIGHOGHOSSIAN, Prof

CONTACT

N

Nathan MEWTON, MD, PhD

CONTACT

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

0

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