Actively Recruiting

Age: 18Years - 45Years
FEMALE
NCT06104748

A Cohort of Maternal Vascular Malperfusion-related FGR (CoMVMFGR)

Led by Shanghai First Maternity and Infant Hospital · Updated on 2024-06-07

500

Participants Needed

1

Research Sites

124 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

Based on a precise diagnostic standard process, through a multicenter study, we will establish a cohort focusing on placenta-mediated fetal growth restriction (FGR). Long-term follow-up will be conducted to seek predictive indicators for short-term and long-term adverse outcomes of maternal vascular malperfusion-related FGR (MVM-FGR).

CONDITIONS

Official Title

A Cohort of Maternal Vascular Malperfusion-related FGR (CoMVMFGR)

Who Can Participate

Age: 18Years - 45Years
FEMALE

Eligibility Criteria

Eligible

You may qualify if you...

  • Singleton pregnancy
  • Diagnosis of fetal growth restriction (FGR) according to the Delphi consensus criteria
  • Early-onset FGR (before 32 weeks) with estimated fetal weight or abdominal circumference below the 3rd percentile; or below the 10th percentile combined with abnormal Doppler readings including uterine artery pulsatility index above the 95th percentile, umbilical artery pulsatility index above the 95th percentile, absent or reversed end-diastolic flow in the umbilical artery
  • Late-onset FGR (32 weeks or later) with estimated fetal weight or abdominal circumference below the 3rd percentile; or at least two of the following: estimated fetal weight or abdominal circumference below the 10th percentile, crossing of growth percentiles by more than 2 quartiles, cerebroplacental ratio below the 5th percentile or umbilical artery pulsatility index above the 95th percentile
  • Provision of signed written informed consent
Not Eligible

You will not qualify if you...

  • Fetus with confirmed genetic disorders related to fetal growth restriction
  • Fetus with confirmed intrauterine infections such as CMV or syphilis
  • Fetus with structural anomalies
  • Incomplete information or absence of informed consent

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Shanghai First Maternity and Infant Hospital

Shanghai, Shanghai Municipality, China, 201204

Actively Recruiting

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Research Team

J

Jianping Chen, Master

CONTACT

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

0

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