Actively Recruiting
Cohort of Prosthetic Joint Infections
Led by Groupe Hospitalier Diaconesses Croix Saint-Simon · Updated on 2022-03-29
800
Participants Needed
1
Research Sites
729 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
Management of prosthetic joint infections (PJI) is a challenging task. These infections include different clinical and microbiological settings calling upon various treatment strategies according to infection type (acute or chronic), bone quality, the involved micro-organism and the patient's general condition and willing. Treatment of PJI combines surgery and prolonged antibiotic therapy. In some patients with a high operative risk prolonged suppressive antibiotic therapy can be used. Lack of large prospective studies motivated the conception of this cohort with a long term follow up, regardless to PJI management procedures.
CONDITIONS
Official Title
Cohort of Prosthetic Joint Infections
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Patient aged over 18 years old with hip, knee and or shoulder joint prosthesis who consented to participate in the study
- Prosthetic joint infection present based on musculoskeletal infection society definition with either one major criterion or four out of six minor criteria
- Major criteria include two positive periprosthetic cultures with identical organisms or a sinus tract communicating with the joint
- Minor criteria include elevated serum C-reactive protein and erythrocyte sedimentation rate, elevated synovial fluid white blood cell count, elevated synovial fluid polymorphonuclear neutrophil percentage, presence of pus in the joint without known cause, positive histological analysis of periprosthetic tissue, or a single positive culture
- Or prosthetic joint infection meeting three criteria: medical history suggesting infection, joint pain for more than 3 months unrelated to mechanical cause, and germ identification in fluid aspiration, tissue culture, or prosthesis sonication fluid culture greater than 50CFU/ml
You will not qualify if you...
- Patient who does not meet eligibility criteria
- Patient lawfully deprived of liberty
- Patient not insured under social security scheme
AI-Screening
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Trial Site Locations
Total: 1 location
1
Groupe Hospitalier Diaconesses Croix Saint Simon
Paris, Île-de-France Region, France, 75020
Actively Recruiting
Research Team
Y
YOUNES KERROUMI, Doctorate
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
0
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