Actively Recruiting
Cohort Study of Clinical and Neuroimaging Characteristics for Benign Paroxysmal Positional Vertigo (BPPV) Patients in China
Led by First Affiliated Hospital Xi'an Jiaotong University · Updated on 2024-02-26
150
Participants Needed
1
Research Sites
13 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
Researchers are conducting an observational study to analyze physical condition abnormalities, mental health, and blood test results in patients with benign paroxysmal positional vertigo (BPPV). The study also aims to create a brain MRI database to identify patients at high risk of residual dizziness and develop a comprehensive system for diagnosing, treating, and recovering from residual dizziness in China. Participants include confirmed BPPV patients and healthy individuals without BPPV. Both groups will undergo behavioral and psychological assessments, blood sample collection, and three brain MRI scans—at the start of the study, and again one month and six months after treatment for BPPV patients. Healthy controls complete these assessments only once at inclusion. During the study, participants will fill out psychological questionnaires, provide blood samples at a local lab, and receive brain MRI scans. Researchers will monitor differences in brain structure and function, vertigo symptoms, and blood markers over time. Additional assessments include fatigue, sleep, cognition, executive function, anxiety, depression, verbal memory, working memory, and auditory attention. The study will run until September 2026.
CONDITIONS
Brief Title
Cohort Study of Clinical and Neuroimaging Characteristics for BPPV Patients in China
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Confirmed diagnosis of benign paroxysmal positional vertigo (BPPV) or healthy individuals without BPPV
- Age between 18 and 60 years
You will not qualify if you...
- History of organic diseases affecting the central nervous system or mental disorders such as tumors, infections, depression, or schizophrenia
- Claustrophobia or discomfort with enclosed spaces that would prevent MRI scans
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Your Study Journey
Duration - 2 to 4 weeks
Participants are screened for eligibility to participate in the trial.
1 visit (in-person) for eligibility confirmation and initial assessments
Duration - Baseline visit
Participants complete behavioral psychological scales, submit blood samples, and undergo brain MRI scans to establish baseline clinical and neuroimaging data.
1 visit (in-person) including psychological assessments, blood sample collection, and brain MRI scan
Duration - 6 months
Participants are followed up with repeated behavioral assessments, blood sampling, and brain MRI scans at 1 month and 6 months to monitor changes in clinical and neuroimaging characteristics.
2 visits (in-person) at 1 month and 6 months for repeated assessments and MRI scans
Trial Site Locations
Total: 1 location
1
The First Affiliated Hospital of Xi'an Jiaotong University
Xi'an, Shaanxi, China, 710061
Actively Recruiting
Research Team
Y
Yuan Wang, M.D.
M
Ming Zhang, PhD
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
2
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