Actively Recruiting
Cohort Study of HIV-positive People, Treated With Long Acting Antiretroviral Therapy
Led by Castagna Antonella · Updated on 2025-05-07
1500
Participants Needed
1
Research Sites
260 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
Systematic, continuative collection of clinical and laboratory data on patients followed at lnfectious Diseases Unit of the IRCCS San Raffaele Hospital in Milan, receiving long-acting ART (Phase IV, single-center, prospective, cohort study) PRIMARY ENDOPOINT: Treatment failure over 48 weeks, defined as virological failure (VF) or therapy discontinuation for any reason (TD) SECONDARY ENDPOINTS: Clinical and pharmacological determinants of efficacy, tolerability, toxicity Modifications in risk and incidence of comorbidities Description of drug-resistance in case of VR Efficacy of rescue regimens in case of VF Quality of life and patient's satisfaction
CONDITIONS
Official Title
Cohort Study of HIV-positive People, Treated With Long Acting Antiretroviral Therapy
Who Can Participate
Eligibility Criteria
You may qualify if you...
- HIV infection
- Age over 18 years
- HIV-RNA less than 50 copies/ml
- Stable antiretroviral therapy
- Planned start of a long-acting regimen approved by AIFA (initially cabotegravir and rilpivirine)
- Written informed consent provided
You will not qualify if you...
- Any contraindication to the use of one or more long-acting drugs according to the drug's technical sheet (including pregnancy, current or planned)
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Ospedale San Raffaele Scientific Institute
Milan, Italy, 20127
Actively Recruiting
Research Team
A
Antonella Castagna, Professor
CONTACT
E
Elisabetta Carini
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
1
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