Actively Recruiting

Age: 18Years - 80Years
All Genders
Healthy Volunteers
NCT05985213

Cohort Study of Inpatients and Outpatient Patients With Cerebral Small Vessel Disease

Led by Shanghai Yueyang Integrated Medicine Hospital · Updated on 2023-08-14

1078

Participants Needed

1

Research Sites

421 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

This cohort study involves the dynamic collection of clinical information, including serum parameters , blood pressure variability, imaging data, and neuropsychological scales, in patients with cerebral small vessel disease (CSVD). The study aims to summarise the clinical and imaging characteristics of the CSVD population and identify novel CSVD risk factors. Additionally, this study intend to uncover the mechanisms underlying the clinical and imaging outcomes of CSVD. Furthermore, a multivariable prediction model for cognitive and mood disorders in patients with CSVD will be established.

CONDITIONS

Official Title

Cohort Study of Inpatients and Outpatient Patients With Cerebral Small Vessel Disease

Who Can Participate

Age: 18Years - 80Years
All Genders
Healthy Volunteers

Eligibility Criteria

Eligible

You may qualify if you...

  • Aged between 18 and 80 years, any gender
  • Completed a 3.0T MRI of the head within the past year meeting 2013 STRIVE imaging criteria
  • Modified Rankin Scale score of 0 to 2 indicating ability to perform daily activities
  • Able to understand and agree to participate, with signed informed consent
Not Eligible

You will not qualify if you...

  • Diagnosed with symptomatic lacunar syndrome within the last 6 months
  • Blood vessel stenosis of 50% or more confirmed by vascular examination
  • Presence of intracranial space-occupying lesions on imaging
  • Diagnosed with other neurological or mental illnesses including stroke (except lacunar infarctions), Parkinson's disease, or Alzheimer's disease
  • Serious illnesses like malignant tumors, heart failure, respiratory failure, renal failure, severe liver dysfunction, severe blood diseases, or gastrointestinal bleeding
  • Severe vision, hearing, language, or limb impairments preventing test completion
  • Pregnant or breastfeeding women
  • Contraindications to MRI scanning such as claustrophobia
  • Other reasons preventing required clinical data collection

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Yueyang Hospital of Integrated Traditional Chinese and Western Medicine, Shanghai University of Traditional Chinese Medicine

Shanghai, China

Actively Recruiting

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Research Team

Y

Yajing Huo

CONTACT

Y

Yan Han

CONTACT

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

1

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