Actively Recruiting
A Prospective, Multicenter Cohort Study of Ischemic Cerebrovascular Disease
Led by Xiangya Hospital of Central South University · Updated on 2023-06-28
5000
Participants Needed
1
Research Sites
52 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
Researchers are conducting a large-scale, multicenter, prospective study to understand ischemic stroke better. The study focuses on collecting various biological samples like blood, feces, and urine from patients diagnosed with ischemic stroke to identify biomarkers linked to the condition. By combining demographic data, clinical indicators, imaging results, and biomarker information, the team aims to create models for risk assessment, early warning, and predicting patient outcomes. The study also seeks to identify key genes and explore related signaling pathways associated with ischemic stroke. Participants receive standard care, which may include intravenous thrombolysis with alteplase administered within the appropriate time window after stroke onset. The study groups include patients categorized based on prognosis as those with favorable or unfavorable outcomes. This observational study tracks patients over time without assigning specific treatments beyond usual care. Participants will undergo regular follow-up assessments, including monitoring cerebrovascular events and evaluating modified Rankin Scale scores three months after stroke onset. Various biological samples are collected to support biomarker analysis. The study involves ongoing data collection on clinical, imaging, and biological parameters to support the development of predictive models. The total duration and specific visit schedules vary by participant, with long-term follow-up planned under the study protocol.
CONDITIONS
Brief Title
a Cohort Study of Ischemic Cerebrovascular Disease
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Clinical diagnosis of ischemic stroke
- Age 18 years or older
- Signed informed consent form
You will not qualify if you...
- Moderate to severe mental disorders or dementia preventing consent and follow-up
- Neurological impairment from migraine aura, epilepsy, or non-ischemic strokes
- Agitation interfering with imaging exams
- Pregnant, lactating, or planning pregnancy within 90 days
- Concurrent malignant tumors or severe diseases with life expectancy under 90 days
- Participation in other clinical studies within 30 days prior to enrollment
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Your Study Journey
Duration - 2 to 4 weeks
Participants are screened for eligibility to participate in the trial.
Duration - 3 months
Participants are observed to monitor cerebrovascular events and functional outcomes after ischemic stroke.
Visits may occur during this period for assessments
Trial Site Locations
Total: 1 location
1
Xiangya Hospital, Central South University
Hunan, China, 410008
Actively Recruiting
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
2
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