Actively Recruiting

Age: 45Years +
All Genders
Healthy Volunteers
NCT07032961

A Cohort Study of Mobile Capsule Gastroscopy for Gastric Pathologies Screening

Led by Nanfang Hospital, Southern Medical University · Updated on 2025-07-04

10000

Participants Needed

1

Research Sites

279 weeks

Total Duration

On this page

Sponsors

N

Nanfang Hospital, Southern Medical University

Lead Sponsor

G

Guangzhou First People's Hospital

Collaborating Sponsor

AI-Summary

What this Trial Is About

The goal of this is to learn about the effectiveness and feasibility of a novel AI- assisted Mobile Capsule Gastroscopy (MCG) system for detecting gastric pathologies in elderly and high-risk populations. The main question it aims to answer is: Can MCG effectively detect gastric pathologies, including common gastric diseases, gastric cancer, and precancerous lesions, in elderly and high-risk individuals at community health centers? Participants will: Epidemiological, diagnostic, and post-MCG follow-up data generated during participants' involvement in the gastric pathologies public screening program will be collected.

CONDITIONS

Official Title

A Cohort Study of Mobile Capsule Gastroscopy for Gastric Pathologies Screening

Who Can Participate

Age: 45Years +
All Genders
Healthy Volunteers

Eligibility Criteria

Eligible

You may qualify if you...

  • Provide written informed consent
  • Be a participant in the 'Gastric Pathologies Screening Programme for the Elderly and High Risk Groups in Guangzhou Municipality'
  • Be a permanent resident of Guangzhou aged 60 years or older who has not had specialized gastric disease screening in the past 3 years
  • Or be aged 45 years or older and meet at least one of the following risk factors: history of Helicobacter pylori infection (positive urea breath test), prior diagnosis of chronic atrophic gastritis, gastric ulcer, neoplastic gastric polyps, hypertrophic gastritis, or pernicious anemia
  • Family history of gastric cancer in a first-degree relative
  • Long-term high-salt diet, history of smoking (20 pack-years or more), or heavy alcohol consumption (100 mL of distilled spirits per day)
Not Eligible

You will not qualify if you...

  • Considered unsuitable for study participation by the investigator
  • Known allergy to medical polymer materials
  • Psychiatric disorders interfering with cooperation
  • Pregnancy or breastfeeding
  • Severe systemic diseases affecting tolerance to examination (such as cardiovascular, respiratory, neurological conditions)
  • Inflammatory bowel diseases like Crohn's disease or ulcerative colitis, or gastrointestinal diverticulosis
  • Known or suspected gastrointestinal malformations, obstructions, strictures, or fistulas
  • Significant difficulty swallowing
  • Acute abdominal symptoms such as pain, vomiting, suspected bowel obstruction, or severe constipation
  • History of major gastrointestinal surgery (e.g., esophagogastrostomy, gastrojejunostomy)
  • Physical weakness preventing body position changes or with concurrent severe illness
  • Medically ineligible for abdominal procedures or refusal to undergo them
  • Deemed unsuitable for Mobile Capsule Gastroscopy by the investigator
  • Refusal to provide informed consent
  • Any other condition making participation unsuitable as judged by the investigator

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Nanfang Hospital, Southern Medical University

Guangzhou, Guangdong, China, 510515

Actively Recruiting

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Research Team

X

Xiaobei Luo

CONTACT

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

1

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