Actively Recruiting

Age: 18Years +
FEMALE
NCT05727085

Cohort of Twin Pregnancy and the Offspring

Led by Fudan University · Updated on 2025-03-14

1000

Participants Needed

1

Research Sites

295 weeks

Total Duration

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AI-Summary

What this Trial Is About

Twin pregnancy increases the risk of maternal and fetal complications, which include gestational hypertension, premature labor, twin-to-twin transfusion syndrome, intrauterine growth restriction, anemia, amniotic fluid abnormalities. Comprehensively understanding the molecular mechanisms of the disease and identification of markers contribute to development of novel therapeutic approaches. In addition, the twin pregnancy, especially the monochorionic, is an essential model of "experiments of nature". This model can be applied to distinguish the epigenetic differences of twins in utero and after birth in the same genomic context. The aim of the study is to constitute a prospective cohort of twin pregnancies and the offspring.

CONDITIONS

Official Title

Cohort of Twin Pregnancy and the Offspring

Who Can Participate

Age: 18Years +
FEMALE

Eligibility Criteria

Eligible

You may qualify if you...

  • Maternal age greater than 18 years old
  • Twin pregnancy
Not Eligible

You will not qualify if you...

  • Presence of fetal chromosomal or congenital abnormalities
  • Stillbirth

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Obstetrics and Gynecology Hospital of Fudan University

Shanghai, Shanghai Municipality, China, 200011

Actively Recruiting

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How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

1

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