Actively Recruiting
Cold and Heat Investigation to Lower Levels of Depression
Led by Barry Sandler · Updated on 2025-11-13
162
Participants Needed
1
Research Sites
150 weeks
Total Duration
On this page
Sponsors
B
Barry Sandler
Lead Sponsor
S
Steadman Philippon Research Institute
Collaborating Sponsor
AI-Summary
What this Trial Is About
This study will recruit 112 medically healthy adults (aged 18-65) currently experiencing depressive symptoms to be randomized to receive either a single Whole Body Hyperthermia (heat therapy) treatment or a Whole Body Hyperthermia treatment followed by a cold water plunge. Participants will complete a baseline assessment of their depressive symptoms as well as 1-week and 2-week post-treatment followup assessments.
CONDITIONS
Official Title
Cold and Heat Investigation to Lower Levels of Depression
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Individuals who currently meet study criteria for depression or individuals who do not currently meet criteria for depression
- English or Spanish speaking (able to provide informed consent and complete questionnaires in one of these languages)
- Able and willing to adhere to trial requirements, including attending all trial visits, preparatory and follow-up sessions, and completing all trial evaluations.
You will not qualify if you...
- Previous adverse reaction to hypothermia, hyperthermia and/or infrared exposure
- Use of any medication that may impact thermoregulatory capacity
- Pregnancy, active lactation, or intention to become pregnant during the study period
- Endorses current active suicidal ideation with a plan or made a suicide attempt in the prior 6 months
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Vail Health Behavioral Health Innovation Center
Edwards, Colorado, United States, 81632
Actively Recruiting
Research Team
S
Study Coordinator
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
DOUBLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
4
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