Actively Recruiting
A Collaborative Intervention for Improving Cancer Pain Management in Cancer Survivors
Led by Mayo Clinic · Updated on 2026-04-13
660
Participants Needed
3
Research Sites
185 weeks
Total Duration
On this page
Sponsors
M
Mayo Clinic
Lead Sponsor
N
National Cancer Institute (NCI)
Collaborating Sponsor
AI-Summary
What this Trial Is About
This clinical trial tests a collaborative pain management intervention (ASCENT) for improving cancer pain in cancer survivors. Cancer pain is prevalent, under-treated, and remains a major cause of suffering, impairment, and disability for millions of Americans. Individual pain interventions and care models show promise for cancer pain in controlled settings. All cancer survivors stand to benefit from electronic health record innovations, as they can experience profound pain outcomes, including marked under- and over-prescribing of opioids. Digitally facilitated solutions are especially helpful and can be customized to address patient needs. The ASCENT intervention provides patients with an educational guide that describes techniques for addressing cancer pain, and uses community health workers and pain care managers to coach patients through a personalized pain management plan. This study may help researchers learn how pain management strategies can improve cancer pain and lower risk of opioid exposure and dependency in cancer survivors.
CONDITIONS
Official Title
A Collaborative Intervention for Improving Cancer Pain Management in Cancer Survivors
Who Can Participate
Eligibility Criteria
You may qualify if you...
- A liquid or solid cancer diagnosis with visits at a Mayo Clinic site in the past 15 years, including malignant hematology such as lymphoma, myeloma, or chronic leukemias
- Age 18 years or older
- Numeric Rating Scale (NRS) pain score of 5 or higher
- Pain developed or worsened after cancer diagnosis
- Meet the description of rural or Hispanic or both
You will not qualify if you...
- Patient Health Questionnaire - 8 (PHQ8) score of 13 or higher
- Enrollment in hospice
- Residence in skilled nursing, inpatient rehabilitation, or long-term care facility
- Palliative Care or Pain Clinic visits in past or upcoming two months
- Any mention of hospice referral in oncology notes
- Confined to bed or chair more than one-third of waking hours
- Currently homeless or do not feel safe at home
- New or worsening chest pain, tightness, or pressure
- Back pain with new/worsening weakness, bowel/bladder control loss, or walking difficulty
- Lightheadedness, inability to keep down food or fluids, or vomiting blood or dark material
- New/worsening headaches with vision changes, nausea, balance, or speech problems
- Positive screen for monthly or more frequent non-cannabis drug use
- Unable to participate due to medical or psychological reasons
AI-Screening
AI-Powered Screening
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Trial Site Locations
Total: 3 locations
1
Mayo Clinic in Arizona
Scottsdale, Arizona, United States, 85259
Actively Recruiting
2
Mayo Clinic in Florida
Jacksonville, Florida, United States, 32224-9980
Actively Recruiting
3
Mayo Clinic in Rochester
Rochester, Minnesota, United States, 55905
Actively Recruiting
Research Team
C
Clinical Trials Referral Office
CONTACT
J
Josiah Lulf
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
SINGLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
SUPPORTIVE_CARE
Number of Arms
2
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